Results 121 to 130 of about 8,812,920 (310)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Rotational training structures and national employment in public health education: an organizational perspective

open access: yesBMC Medical Education
Introduction Postgraduate medical education (PGME) relies on structured training rotations and workplace-based learning (WBL) to provide comprehensive clinical training and professional development.
Nadieh J. L. M. Taks   +4 more
doaj   +1 more source

A visual thesis? techniques for reporting practice-led research [PDF]

open access: yes, 2001
This paper describes an approach taken to the use of visual material as a significant part of PhD thesis in an Industrial Design research project. The aspiration to make creative work central to the thesis has been debated in a wide range of disciplines,
Rust, C., Wilson, A.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The enhancement of technology education classroom practice in New Zealand [PDF]

open access: yes, 2001
This paper reports on a number of New Zealand technology education research studies undertaken over seven years by researchers in the Centre for Science and Technology Education Research centred upon examining and enhancing classroom practice.
Jones, Alister, Moreland, Judy
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

"Can the Research-Practice Gap Ever Really be Bridged? Applying the ‘Applied’ in Evidence-Based Organisational Practice" [PDF]

open access: yes
Applied Occupational Psychology research provides a valuable evidence base which can potentially be used to inform and improve organisational practice. In reality, however, its actual usage in organisational practice is not a given.
Francis-Smythe, Jan, Watts, Helen
core  

Releasing the power: research led learning in a professional practice undergraduate curriculum [PDF]

open access: yes, 2009
There is a challenge for vocational programmes in Higher Education in addressing the needs of a practice based discipline while developing enquiry based abilities in students.
Daws, Michael   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Suicidal thoughts and behaviours in pre-adolescent children: a population-based study in Olmsted County, Minnesota

open access: yesBMJ Open
Objectives To describe the incidence, presentation and long-term health outcomes of suicidal thoughts and behaviours (STBs) in children aged 12 years or under.Methods This population-based study included children identified through the Rochester ...
Mohammad Hassan Murad   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy