Results 151 to 160 of about 55,271,543 (296)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Caratteristiche costruttive e di funzionamento dei LED

open access: yes, 2011
In questa comunicazione dono descritti i LED, le principali tipologie presenti oggi sul mercato, i punti di forza e di debolezza, la loro alimentazione, le ottiche, le tecniche per ottenere luce bianca, il controllo della temperatura di giunzione, nonchè
BELLIA, LAURA
core  

A Practice-Led Research Methodology for Contemporary Music Higher Education: A standards-oriented framework for supervising and assessing undergraduate practice-led research

open access: yes
This white paper proposes a standards-oriented methodological framework for supervising and assessing undergraduate practice-led research in contemporary music higher education. It addresses recurring supervisory and examination challenges arising when artistic practice functions as the primary site of inquiry rather than as illustrative output.
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Research-led practice in design research used to best demonstrate design theories

open access: yes, 2014
There is contention in the design research community surrounding the legitimacy of industrial design practice used in design research in academia. This study claims that research-led practice in design research within the context of universities through ...
Thong, C (15772163)   +3 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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