Results 71 to 80 of about 4,642,674 (246)

Trade Facilitation Negotiations in the WTO: Implications for Bangladesh and Other Least Developed and Developing Countries [PDF]

open access: yes
This paper provides an overview of how trade facilitation has been addressed in the WTO to date, and how this may affect Bangladesh’s negotiating strategy on trade facilitation in the upcoming Cancun Ministerial and beyond.
Wenguo Cai, Sarah Geddes
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Towards an explicit modeling of trade facilitation in CGE models: evidence from Egypt [PDF]

open access: yes
This paper develops a dynamic computable general equilibrium (CGE) model incorporating trade facilitation aspects. This paper’s contributions are twofold: theoretical and empirical.
Zaki, Chahir
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Quantifying the Benefits of Trade Facilitation in ASEAN [PDF]

open access: yes
This paper assesses the performance and progress of the ASEAN economies in trade facilitation, and the effect of improved trade facilitation on the regionfs manufacturing trade with a focus on port efficiency, customs environment, regulatory environment ...
Tsunehiro Otsuki
core  

Settlement Facilitation by Arbitral Tribunals: Boosting Efficiency or Endangering Due Process Rights?

open access: yesAnali Pravnog Fakulteta u Beogradu
The paper explores the concept of settlement facilitation by arbitral tribunals. After a brief overview of the relevant legislation regarding this practice, the paper focuses on different facilitating settlement measures that are available to arbitral ...
MARKO DOŠLIĆ
doaj   +1 more source

Developing a facilitation model to promote organisational development in primary care practices

open access: yesBMC Family Practice, 2006
Background The relationship between effective organisation of general practices and health improvement is widely accepted. The Maturity Matrix is an instrument designed to assess organisational development in general practice settings and to stimulate ...
Elwyn Glyn   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Need for and Cost of Selected Trade Facilitation Measure Relevant to the WTO Trade Facilitation Negotiations: A Case Study of Nepal [PDF]

open access: yes
Trade facilitation has been a longstanding and traditional feature of GATT, which is expected to have serious implication for developing member countries.
Pushpa Raj Rajkarnikar
core  

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