Results 241 to 250 of about 301,813 (312)

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Action Collaborative on Traumatic Brain Injury Care: Adapted Clinical Practice Guideline. [PDF]

Ann Fam Med
Silverberg ND, Lee K, Mikolić A, Bayley MT, Brody DL, Ely EW, Giacino JT, Halabi C, Hammond FM, Ignacio DA, Mosti C, van der Naalt J, Pappadis MR, Ravi A, Tenovuo O, Wang VY, Verduzco-Gutierrez M, Manley GT, Action Collaborative on TBI Care.   +18 more
europepmc   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Clinical practice guideline for pediatric scar prevention and treatment (2025 edition). [PDF]

Burns Trauma
Chinese Burn Association.
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Correction: Clinical practice guideline for the treatment of Sjögren's disease through off-label drug use in China (English edition). [PDF]

Clin Rheumatol
Mo Y, Yang W, Li Y, Dai L, Committee for Rheumatologists, Immunologists of the Chinese Primary Health Care Foundation.   +5 more
europepmc   +1 more source

Clinical Practice Guideline Recommendations for Post-Acute Sequelae of COVID-19. [PDF]

Infect Chemother
Seo JW, Seo YB, Kim SE, Kim Y, Kim EJ, Kim T, Kim T, Lee SH, Lee E, Lee J, Jeong YH, Jung YH, Choi YJ, Song JY.   +13 more
europepmc   +1 more source

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of renal cell carcinoma, version 3.0. [PDF]

J Immunother Cancer
McKay RR, Ajmera A, Atkins MB, Barata PC, Bergerot C, Bukavina L, Choueiri TK, Desai A, Hakimi AA, Poteat S, Powles T, Rini BI, Shuch B, Signoretti S, Siva S, Xu W, Yip W, Zhang T, Pal SK.   +18 more
europepmc   +1 more source

ESMO Clinical Practice Guideline Express Update on the adoption of physical exercise in patients with localised colon cancer. [PDF]

ESMO Open
Pentheroudakis G, Argilés G, Arnold D, Smyth E, Ducreux M, ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org.   +5 more
europepmc   +1 more source