Results 171 to 180 of about 6,842,225 (303)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

A Computational Method for Systematic Comparison of Clinical Practice Guidelines. [PDF]

Clin Public Health Guidel
Ebben KCWJ, Swinkels ACP, de Kroon CD, Schmeink CE, Koh WJ, van der Hel OL, van Vegchel T, Thissen M, de Hingh IHJT, van der Werf J.   +9 more
europepmc   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

A systematic scoping review on quality criteria for clinical practice guidelines for rare diseases. [PDF]

Syst Rev
Hieltjes IJ, Haneveld MJK, Van Dusseldorp I, Gaasterland CMW, van der Lee JH.   +4 more
europepmc   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Closing the Guideline Gap

JACC: Advances
Rohan G. Reddy, BS, David A. Danford, MD, MPH, Andreas Schuster, MD, PhD, MBA, Shelby Kutty, MD, PhD, MHCM   +3 more
doaj   +1 more source

The Semmelweis Framework: structuring evidence foundations and expert opinion in clinical practice guidelines. [PDF]

BMC Med Res Methodol
Nagavci B, Andrews MR, Vikse J, Studenic P, Stamm T, Lakatos B.   +5 more
europepmc   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Implementation of guidelines on delirium and assessment of their impact on clinical practice in an acute care general hospital

, 2007
Berney, Alexandre, Taffé, Patrick, Michaud, Laurent, Stiefel, Friedrich, Burnand, Bernard, Ruffieux, Christiane, Dorogi, Yves, Voellinger, Rachel, Michel, Patrik   +8 more
core   +1 more source

Editorial for clinical practice guidelines issue. [PDF]

Indian J Psychiatry
Sarkhel S.
europepmc   +1 more source