Results 101 to 110 of about 6,040,142 (299)

Medical Treatment for Peyronie’s Disease: Systematic Review and Network Bayesian Meta-Analysis

open access: yesThe World Journal of Men's Health
Purpose: To investigate the efficacy of medical treatment options for Peyronie's disease (PD) including oral drugs, intralesional treatment and mechanical treatment compared with placebo treatment using network meta-analysis (NMA).
Hyun Young Lee   +3 more
doaj   +1 more source

What are communities of practice? A comparative review of four seminal works

open access: yes, 2005
This paper is a comparative review of four seminal works on communities of practice. It is argued that the ambiguities of the terms community and practice are a source of the concept's reusability allowing it to be reappropriated for different purposes ...
A. Cox   +36 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Moral Economy and Research on Projects: neglect and relevance to social capital and competencies [PDF]

open access: yes, 2006
This paper makes a theoretical contribution to the understanding of management and of projects. The paper adopts an analysis of the moral economy, which poses a conceptual challenge to the way in which management generally, and specifically concerning ...
Pryke, S, Smyth, H
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Economic Analysis of Management Practices to Reduce Phosphorus Load to Lake Eucha and Spavinaw [PDF]

open access: yes
Changes in management practices are often proposed to reduce phosphorus loading from a watershed due to over application of poultry litter. This study determines the choice, location, and level of each best management practice in the watershed to meet a ...
Howry, Sierra S.   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Facilities Management Approach For Achieving Sustainability in Commercial Buildings in Nigeria [PDF]

open access: yes, 2014
The purpose of this research is to determine the extent of sustainable facilities management (FM) practice in the management of commercial buildings in Nigeria and identify barriers to it, in order to develop a solution model that will proffer ways of ...
Akintoye, Akintola   +3 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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