Results 151 to 160 of about 1,505,240 (268)

Surge capacity and practice management challenges of Canadian family physicians during COVID-19: a qualitative study. [PDF]

Hum Resour Health
Mathews M, Ryan D, Hedden L, Lukewich J, Marshall EG, Gill P, Wetmore SJ, Meredith L, Spencer S, Brown JB, Freeman TR.   +10 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

General practice management after transition events: protocol for an experience-based co-design study. [PDF]

BJGP Open
Shariff Z, Dale J, Spencer RA.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The Use of a Three-in-One Practice-Management-Innovation Training Model in the Construction of an Infection Control Team. [PDF]

Risk Manag Healthc Policy, 2021
Min Q, Yang J, Gong X.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Clinical Hints: Referral for Minor Surgery

Australasian Orthodontic Journal, 1990
Jacobs Stanley G.
doaj   +1 more source

N-acetylcysteine (NAC) and Its Role in Clinical Practice Management of Cystic Fibrosis (CF): A Review. [PDF]

Pharmaceuticals (Basel), 2022
Guerini M, Condrò G, Friuli V, Maggi L, Perugini P.   +4 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Resuscitative Endovascular Balloon Occlusion of the Aorta in surgical and trauma patients: a systematic review, meta-analysis and practice management guideline from the Eastern Association for the Surgery of Trauma. [PDF]

Trauma Surg Acute Care Open
Harfouche MN, Bugaev N, Como JJ, Fraser DR, McNickle AG, Golani G, Johnson BP, Hojman H, Abdel-Aziz H, Sawhney JS, Cullinane DC, Lorch S, Haut ER, Fox N, Magder LS, Kasotakis G.   +15 more
europepmc   +1 more source