Results 141 to 150 of about 3,737,851 (258)

Emerging patterns of school leadership: current practice and future directions [PDF]

core  

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome. [PDF]

Clin Endocrinol (Oxf)
Behary P, Raveendran D, Nair R, Di Marco A, Papadopoulou D, Wernig F, Abbara A, Meeran K, Martin N, Cox J, Comninos AN.   +10 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Annual Report: 2018 to 2019: Patterns in practice, key messages, and 2020 work programme [PDF]

, 2020

core  

PD-L1 Negative Advanced Non-Small Cell Lung Cancer: Practice Patterns and Real-World Outcomes. [PDF]

Curr Oncol
Bégin AA, Dubé-Pelletier M, Labbé C, Mai V, Maranda-Robitaille M, Denault MH.   +5 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Practice Patterns and Trends in Temperature Control After Cardiac Arrest: A Multi-Specialty Survey. [PDF]

J Clin Med
Carr CT, Eckert MB, Bhakta N, Guirgis FW, Hopson C, Maciel CB, Becker TK.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Preferred practice patterns in the management of keratoconus: a national survey of cornea specialists in Saudi Arabia. [PDF]

BMC Ophthalmol
AlJohani S, Othman AYA, Khathami AA, Alshehri A.   +3 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source