Results 231 to 240 of about 3,701,556 (301)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Stereotactic radiosurgery for brain metastases: evolving practice patterns from the national cancer database (2004-2020). [PDF]

J Neurooncol
Shih JJ, Jain B, Patel R, Jain U, Lam M, Chino F, Patel MI, Dee EC, Pollom E, Li G, Taparra K.   +10 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Trends in lumbar epidural injection selection: A survey of practitioner preferences and practice patterns. [PDF]

Interv Pain Med
Triglia R, Walrond A, Wagner J, Kitei PM, Boyd J, Simon JI.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Redefining Early Diabetic Kidney Disease Management: A Critical Review of Practice Patterns and Missed Opportunities in Real-World Settings. [PDF]

Cureus
Almalki A.
europepmc   +1 more source

Temporal Trends and Practice Patterns Associated With Utilization of Catheter-Based Interventions for Pulmonary Embolism. [PDF]

J Soc Cardiovasc Angiogr Interv
Watson NW, Jaff MR, Carroll BJ, Orui H, Li S, Song Y, Weinstein JL, Yeh RW, Secemsky EA.   +8 more
europepmc   +1 more source

Submicrobial Dosing of Antibiotics in Dermatology: A Survey of Real World Practice Patterns. [PDF]

Australas J Dermatol
Zou H, Tabatabaei E, Johnson JH, Daveluy S.   +3 more
europepmc   +1 more source

Changes of Clinical Practice Patterns of Allergen Immunotherapy in Korea. [PDF]

Allergy Asthma Immunol Res
Lee HY, Kang SY, Kim K, Kim JH, Ryu G, Min JY, Park KH, Park SY, Sung M, Lee Y, Yang EA, Jee HM, Ha EK, Shin YS, Lee YW, Chung EH, Choi SH, Koh YI, Kim ST, Nahm DH, Park JW, Shim JY, Han DH, Han MY, Lee SM, Choi JH, Korean Academy of Asthma Allergy and Clinical Immunology (KAAACI) working group on Allergen Immunotherapy and Allergen.   +26 more
europepmc   +1 more source

Ominous practice pattern.

Canadian family physician Medecin de famille canadien, 1997
openaire   +1 more source