Results 91 to 100 of about 5,316,664 (300)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Middle-Level Teacher Development and Identity: A Review of the Literature

open access: yesEducation Sciences
Historically, the field of middle-level education has taken it as a given that teachers of young adolescents should be specially prepared to teach in the middle grades, developing a teacher identity that centers around responding to and advocating for ...
P. Gayle Andrews, Alyson Leigh Wright
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

'To Make the Enemy Immortal by the Sheer Play on Words' – on Julian Tuwim’s Pamphlets

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2016
The article presents both the formal aspects of the poetics of Tuwim’s pamphlets (enumeration, hyperbole, grotesque, irony) and the figures of those who are the targets of his satirical addresses.
Tomasz Stępień
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Slideshow: Future Architects Put Market Theory into Practice [PDF]

open access: yes, 2014
From evaluating locations to rendering creative designs and a cost analysis, graduate architecture students help envision a food hub and events space for ...
Rodrigues, Jill
core   +1 more source

Nonlinear Regge Trajectories in Theory and Practice

open access: yes, 2008
The problems related to nonlinear behavior of Regge trajectories (RT) and their renormalization group invariance are discussed.Comment: The extended version of the talk at the International Workshop Diffraction-2008 (La Londe-les-Maures, France ...
A. A. Godizov   +5 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Constructing a Theory of Educational Administration [PDF]

open access: yes, 2018
The development of administrative theory has long been a quest for scholars in the field of educational administration. The beginnings of the development of a theory of educational administration began with Griffiths‘ (1959) now classic Administrative ...
Beach, Don M.
core   +1 more source

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