Results 101 to 110 of about 3,459,336 (315)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
DEVELOPMENT OF TECHNOLOGY AND METHODS OF CONTROL OF BIFUNCTIONAL OINTMENT
Разработка и регистрация лекарственных средств, 2019 A new bifunctional ointment with chondroitin sulfate and celecoxib on a hydrophilic base was developed. The optimum conditions of the technology and technological properties of the ointment were determined.
K. R. Saveleva +5 more
doaj
Dairy Manure Management - Spreading Equipment (NDPC 27.7)
, 1977 This 4 page fact sheet (NDPC-27.7) was originally published by the Northeast Dairy Practices Council (NDPC) and the Northeast Regional Agricultural Engineering Service (NRAES, later known as the Natural Resource, Agriculture, and Engineering Service), a ...
Northeast Dairy Practices Council +1 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Activities of the oral health teams in primary health care: a time-motion study
BMC Health Services ResearchBackground Efficient planning of the oral health workforce in Primary Health Care (PHC) is paramount to ensure equitable community access to services. This requires a meticulous examination of the population’s needs, strategic distribution of oral health
Lorrayne Belotti +7 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
International Journal of General MedicineAbeer Abdulhadi Alhuthali,1 Abdullah Alshammari,2 Athar Yosuf Jaha,2 Alaa Shahbar,2 Lama Mohammed Almilaibi,3 Reem Saeed Alwadie,2 Alanoud Naher Alghanmi,3 Manal Aljohani,4 Abdullah F Alharthi,5 Mohammed Alnuhait5 1Department of Pharmaceutical Care ...
Alhuthali AA +9 more
doaj
The Pan African Medical Journal, 2013 Buruli ulcer (BU) is a cutaneous neglected tropical disease caused by Mycobacterium ulcerans. Participation of Community Health Workers (CHWs) is an integral part of the management of BU, yet their impact has not been systematically evaluated in sub ...
Marius Zambou Vouking +2 more
doaj +1 more source
Emergency Architectures. Approaching Methodologies for a Rapidly Changing Environment
Emergency Architectures presents an atlas-based methodological framework through which Estefania Mompean Botias composes diverse narrative accounts in order to reassemble meanings and articulate methodologies of recomposition.
Riesinger, Karen +4 more
core
Dairy Manure Management - Solid Manure Storage (NDPC 27.5)
, 1977 This 4 page fact sheet (NDPC-27.5) was originally published by the Northeast Dairy Practices Council (NDPC) and the Northeast Regional Agricultural Engineering Service (NRAES, later known as the Natural Resource, Agriculture, and Engineering Service), a ...
Northeast Dairy Practices Council +1 more
core