Results 191 to 200 of about 8,841,562 (288)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Provider insight on surmounting specialty practice challenges to improve Tdap immunization rates among pregnant women

, 2018
Arpita Mehrotra, Allison Fisher, Jennifer Mullen, Leslie Rodríguez, Angela J. Jiles, Alison P. Albert, Laura Randall, Paula M. Frew   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Suicide ideation, suicide risk, and firearm storage practices and attitudes among U.S. uniformed law enforcement officers'. [PDF]

Psychiatry Res
LeDuc M, Cary J, Marvin C, Mitchell SM.
europepmc   +1 more source

Physician smoking cessation counseling and adherence to the Clinical Practice Guideline

, 2014
Sofie Champassak, Delwyn Catley, Sarah Finocchario‐Kessler, Maghen Farris, Maniza Ehtesham, Rachel Schoor, Kathy Goggin   +6 more
openalex   +1 more source

The Effects of Human Resource Management Practices on Productivity

, 1995
Casey Ichniowski, K. L. Shaw, Giovanna Prennushi   +2 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Knowledge and prevention practices regarding cytomegalovirus among pregnant women in Gondar city a multicenter cross-sectional study. [PDF]

Sci Rep
Ayele HS, Beyna AT, Asrie AB, Belete TM, Bekalu AF, Gelaye AT, Tadesse G, Bizuneh GK, Getachew D, Mengesha AK.   +9 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Cultural Guideposts of Health: A crisis response evaluation framework for California's diverse Indigenous communities. [PDF]

J Public Health Res
Armenta-Belen K, Rey L, Severns J, Dickerson D, Hedrick V, Miele G, Bhakta M, Rutkowski B, Freese T, Guiding Coalition of Traditional Healers and Knowledge Keepers.   +9 more
europepmc   +1 more source