Results 71 to 80 of about 1,540,437 (219)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Activities of the oral health teams in primary health care: a time-motion study

BMC Health Services Research
Background Efficient planning of the oral health workforce in Primary Health Care (PHC) is paramount to ensure equitable community access to services. This requires a meticulous examination of the population’s needs, strategic distribution of oral health
Lorrayne Belotti, Sofia Maito, Andrea Liliana Vesga-Varela, Leticia Yamawaka de Almeida, Maira Tamires da Silva, Ana Estela Haddad, Danielle da Costa Palacio, Daiana Bonfim   +7 more
doaj   +1 more source

Bioherbicides and agroecology: challenges and opportunities for agroecological weed management

Frontiers in Agronomy
The limited availability of herbicides for weed management, coupled with the rapid expansion of herbicide-resistant weed populations, has intensified the need to explore alternative weed management strategies, particularly for producers transitioning to ...
Milos Zaric, Vesna Dragičević, Milena Simić, Natalija Pavlović, Milan Brankov   +4 more
doaj   +1 more source

The impact of community health workers (CHWs) on Buruli ulcer in sub-Saharan Africa: a systematic review

The Pan African Medical Journal, 2013
Buruli ulcer (BU) is a cutaneous neglected tropical disease caused by Mycobacterium ulcerans. Participation of Community Health Workers (CHWs) is an integral part of the management of BU, yet their impact has not been systematically evaluated in sub ...
Marius Zambou Vouking, Violette Claire Tamo, Lawrence Mbuagbaw   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Real-World Safety of Trastuzumab Deruxtecan in Patients with HER2-Positive and HER2-Low Metastatic Breast Cancer in Saudi Arabia: A Retrospective Cohort Study

International Journal of General Medicine
Abeer Abdulhadi Alhuthali,1 Abdullah Alshammari,2 Athar Yosuf Jaha,2 Alaa Shahbar,2 Lama Mohammed Almilaibi,3 Reem Saeed Alwadie,2 Alanoud Naher Alghanmi,3 Manal Aljohani,4 Abdullah F Alharthi,5 Mohammed Alnuhait5 1Department of Pharmaceutical Care ...
Alhuthali AA, Alshammari A, Jaha AY, Shahbar A, Almilaibi LM, Alwadie RS, Alghanmi AN, Aljohani M, Alharthi AF, Alnuhait M   +9 more
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Chemotherapy-Induced Toxicities in Pediatric Cancer Patients: A Cross-Sectional Survey Using a Child- and Caregiver-Reported Outcome Tool in Tanzania

Drug, Healthcare and Patient Safety
Deogratias M Katabalo,1,2 Esther Njile,1 Benson R Kidenya,3 Anthony Cuthbert Liwa,4 Kristin Schroeder2,5 1Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences, Mwanza, Tanzania ...
Katabalo DM, Njile E, Kidenya BR, Liwa AC, Schroeder K   +4 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source