Results 111 to 120 of about 24,669 (243)

The Recruitment and Retention of Individuals With Intellectual Disability in Randomized Controlled Trials: A Scoping Review

British Journal of Learning Disabilities, Volume 54, Issue 2, Page 171-211, June 2026.
ABSTRACT Background People with intellectual disabilities face significant health disparities and often encounter barriers in accessing healthcare services. Although research supports the need for reasonable adjustments to improve healthcare access for this population, implementation in acute healthcare settings remains limited.
Owen Doody, Louise Murphy, Ruth Ryan, Rosemary Lyons, Wenyi Tang, Lorna Bourke   +5 more
wiley   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, Volume 183, Issue 12, Page 3213-3233, June 2026.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Association of Growth Hormone Adherence and Growth Outcomes in Paediatric Patients: Results From a Clinical Registry

Clinical Endocrinology, Volume 104, Issue 6, Page 603-611, June 2026.
ABSTRACT Objective Daily growth hormone (GH) therapy for growth disorders requires long‐term adherence. The aim of this study was to investigate the association of adherence with 2‐year growth outcomes in paediatric patients receiving daily GH therapy in a clinical registry. Design Retrospective cohort study. Patients Patients with growth disorder were
Tilman Robert Rohrer, Klaus Hartmann, Peter Herbert Kann, Tobias Vogelmann, Dorna Hogeabri, Tino Schubert   +5 more
wiley   +1 more source

SEMASEARCH Study Design: Real‐World Evaluation of Semaglutide 2.4 mg in Adults With Severe Obesity Underrepresented in Clinical Trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4602-4609, June 2026.
ABSTRACT Background Although semaglutide 2.4 mg has demonstrated significant weight loss efficacy in clinical trials, real‐world data, particularly with regard to clinically complex and underrepresented populations, remain limited. Objectives The study aims to assess the real‐world effectiveness and patient‐reported outcomes associated with the use of ...
Pierre Bel Lassen, David Jacobi, Marie‐Claude Brindisi, Jean‐Baptiste Bonnet, Fabien Subtil, Sylvie Bin, Fanny Abad, Christine Poitou, Bérénice Segrestin, Séverine Ledoux, Bénédicte Gaborit, Judith Aron‐Wisnewsky, Claire Carette, Mohamed Zerguine, Blandine Gatta‐Cherifi, Didier Quilliot, Emilie Montastier, Antoine Avignon, Héléna Mosbah, Sébastien Czernichow, Emmanuel Disse   +20 more
wiley   +1 more source

Behavioral Profile of Children and Adolescents with Prader-Willi Syndrome and Exogenous Obesity

Psicologia, 2009
The objective of present study was compared the behavioral profile of two different groups of children and adolescents with obesity. Ten subjects presented diagnoses of exogenous obesity and ten Prader-Willi syndrome.
Yara Garzuzi, Luiz Renato Rodrigues Carreiro, José Salomão Schwartzman, Maria Luiza Guedes de Mesquita, Domingos Palma, Fábio Ancona Lopez, Denise Ely Bellotto de Moraes, Elizeu Coutinho de Macedo, Maria Cristina Triguero Veloz Teixeira   +8 more
doaj  

Continued Involvement: A Scoping Review on Family Members' Needs and Experiences Collaborating With Support Staff for Relatives With Intellectual Disabilities Living Outside the Family Home

Journal of Intellectual Disability Research, Volume 70, Issue 6, Page 561-578, June 2026.
ABSTRACT Background Family members' involvement in the care for their relative often continues after their relative has moved out of the family home. However, little is known about the needs of family members when collaborating specifically with support staff caring for their relative.
Frances R. Vereijken, Noud Frielink, Andrew Jahoda, Petri J. C. M. Embregts   +3 more
wiley   +1 more source

Prader-Willi Syndrome. About a Case

Revista Finlay, 2021
Prader-Willi syndrome is a rare genetic disease, characterized by hypothalamic-pituitary anomalies, which presents with severe hypotonia during the neonatal period and the first two years of life, with hyperphagia with a high risk of developing morbid ...
Carlos Enrique Cruz Carrazana, Claudia García Carrazana   +1 more
doaj  

Values of Individuals With Rare Genetic Neurodevelopmental Disorders and Their Family/Caregivers in Healthcare: A Scoping Review to Inform Guideline Development

Journal of Intellectual Disability Research, Volume 70, Issue 6, Page 608-652, June 2026.
ABSTRACT Background Healthcare decision‐making for individuals with rare genetic neurodevelopmental disorders (RGNDs) associated with intellectual disabilities (ID) can be complex due to the intersection of lifelong care needs, limited medical expertise and communication barriers.
Mirthe J. Klein Haneveld, Louise Cox, Petri J. C. M. Embregts, Alistair R. Niemeijer, Martina C. Cornel, Charlotte M. W. Gaasterland, Agnies M. van Eeghen   +6 more
wiley   +1 more source

Lack of evidence for monosomy 1p36 in patients with Prader-Willi-like phenotype

Brazilian Journal of Medical and Biological Research, 2008
Monosomy 1p36 is the most common subtelomeric microdeletion syndrome with an incidence rate estimated to be 1 in 5000 births. A hypothesis of a similarity between patients with 1p36 deletion and those with Prader-Willi syndrome and the existence of two ...
V.R. Rodríguez, L.F. Mazzucato, J.M. Pina-Neto   +2 more
doaj  

Central precocious puberty and risk of atopic diseases: The mediating role of obesity and sex hormones

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
Abstract Background Atopic diseases, including atopic dermatitis, allergic rhinitis, and asthma, are complex inflammatory conditions with increasing prevalence in children. Central precocious puberty (CPP) has also become increasingly common. The potential role of CPP in atopic diseases remains unclear.
Yung‐Han Lai, Yu Hsiang Liu, Hsiao‐Chi Chuang, Nguyen Thi Kim Anh, Hsin‐Yuan Chang, Yang‐Chin Chen   +5 more
wiley   +1 more source