Results 231 to 240 of about 1,049,733 (313)

Interaction Between Chronotype and the Timing of Antihypertensive Medication on Cardiovascular Events and Death

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Scott R. Garrison, Jeffrey A. Bakal, Michael R. Kolber, Christina S. Korownyk, Lee A. Green, Jessica E. M. Kirkwood, Finlay A. McAlister, Raj S. Padwal, Richard Lewanczuk, Michael D. Hill, Alexander G. Singer, Alan Katz, Michael D. Kelmer, Armine Gayayan, Farah N. Campbell, Ana Vucenovic, Nathan R. Archibald, Jack M. S. Yeung, Erik R. E. Youngson, Kimberlyn McGrail, Braden G. O’Neill, Michelle Greiver, Donna P. Manca, Ting Wang, Braden J. Manns, Dee A. Mangin, Cathy MacLean, James McCormack, Sabrina T. Wong, Colleen Norris, G. Michael Allan   +30 more
doaj   +1 more source

[Preface to the Special Issue on 'Pragmatic Cardiovascular Imaging']. [PDF]

J Korean Soc Radiol
Lee J.
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

EPVs: lists for evaluation of pragmatic skills [PDF]

, 2012
Cocquyt, Mie, Zink, Inge
core   +1 more source

The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care. [PDF]

BJU Int
Sharma A, Campbell T, Kanabar S, Soanes H, Sathanapally G, Bates A, John R, Adams C, Brassill A, Lennon B, Sinha S, Flaxman L, von Hasseln V, Camilleri P, Sabharwal A, Charlton P, Andrade G, Tuthill M, Protheroe A, Lamb AD, Leslie T, Leiblich A, Lopez F, Verrill C, Gleeson F, MacPherson R, Hamdy FC, Bell R, Bryant RJ.   +28 more
europepmc   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Integrated Nurse Care Management to Reduce Pain Interference for Primary Care Patients in Rural Communities: Results from a Pilot Study. [PDF]

Pain Med
Tong ST, Keiser B, Cortez K, Hoffman E, Wang J, Stephens KA, Welch SS, Tapp H, Holtzer C, Reeves KW, Jawort S, Humbert AT, Belza B, Ludden T, Ang DC, Patel KV.   +15 more
europepmc   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source