The Role of Social Media Interaction in Developing Intercultural Digital Communication Competence: A Systematic Literature Review. [PDF]
Behav Sci (Basel)Zhang C, Husain S, Mamat R.
europepmc +1 more source
A Modified Anatomical All‐Inside Double‐Bundle Anterior Cruciate Ligament Reconstruction Technique
Arthroscopy Techniques, EarlyView.Abstract Arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) is the standard surgical treatment for ACL injuries and is most commonly performed using anatomical single‐bundle (SB) or double‐bundle (DB) techniques. With the development of the all‐inside technique, the all‐inside SB technique using socket‐based tunnels and cortical ...
Hanting Yi +6 more
wiley +1 more source
Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)
British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul +7 more
wiley +1 more source
Optimizing scalable approaches for early detection of cognitive impairment in primary care. [PDF]
Alzheimers Dement (Amst)Owora AH +12 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink +9 more
wiley +1 more source
An Explainable AI Framework for Continuous Monitoring, Risk Stratification, and Clinical Decision Support in Primary Biliary Cholangitis: Protocol for a Multiphase Development and Validation Study. [PDF]
JMIR Res ProtocNjei B, Sidney Kanmounye U.
europepmc +1 more source
Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors
British Journal of Clinical Pharmacology, EarlyView.Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem +5 more
wiley +1 more source
A framework for clinical validation of generative artificial intelligence therapeutics. [PDF]
World PsychiatryGalatzer-Levy IR +3 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari +6 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen +4 more
wiley +1 more source