Results 51 to 60 of about 26,676 (258)
DISKURSMARKER IN DER INTERIMSPRACHE BEI DEUTSCHSTUDIERENDEN IN DER REPUBLIK NORDMAZEDONIEN / English Title: DISCOURSE MARKERS IN THE INTERLANGUAGE BY STUDENTS OF GERMAN IN THE REPUBLIC OF NORTH MACEDONIA [PDF]
Journal of Languages for Specific Purposes, 2023 The study presented in this paper is part of a research project entitled “The role of explicit instructions in developing pragmatic competence in learning English and German as a foreign language,” currently being conducted at the “Goce Delchev ...
Biljana Ivanovska, Gzim Xhaferri
doaj
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
Pragmatic markers and ideological positioning in EUROPARL: A corpus-based study
Russian Journal of LinguisticsPolitical persuasion in institutional contexts often relies on subtle linguistic cues rather than overt argumentation. While Critical Discourse Analysis (CDA) has extensively examined macro-level ideological strategies, the micro-pragmatic mechanisms ...
Péter Bálint Furkó
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Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
“Not gonna lie, that’s a real bummer”—The Usualization of the Pragmatic Marker not gonna lie
LanguagesThis study is concerned with the formal and functional development of the pragmatic marker not gonna lie. It comprises a detailed investigation into the usage and development of not gonna lie in American English.
Nicole Benker
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Pragmatics. Quarterly Publication of the International Pragmatics Association (IPrA), 2022 openaire +1 more source
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Discours, 2018 This paper attempts to describe how adverbs and adverbial expressions of manner and space came to function as discourse markers of topic shifting in contemporary Romanian and to sketch a possible typology of these markers.
Alice Ionescu, Cecilia-Mihaela Popescu
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