Results 51 to 60 of about 9,170 (266)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

What Drives Multi-Chain Crypto Forecasting: Model Choice, Feature Selection, and Transferability

open access: yesMathematics
Increasingly shaped by heterogeneous on-chain activity rather than a single shared market process, this study investigates 7-day-ahead forecasting using 147 market and on-chain indicators across eight major blockchain ecosystems from October 2023 to ...
Mingxing Wang   +3 more
doaj   +1 more source

REINTERPRETASI KETIDAKSANTUNAN PRAGMATIK

open access: yesKajian Linguistik dan Sastra, 2017
Enormous imbalance of study between language impoliteness and language politeness has become serious concern among those who regard pragmatics important field in language learning.
R. Kunjana Rahardi
doaj   +1 more source

A pragmatic view on pragmatic trials

open access: yesDialogues in Clinical Neuroscience, 2011
Clinical trials have been the main tool used by the health sciences community to test and evaluate interventions, Trials can fall into two broad categories: pragmatic and explanatory. Pragmatic trials are designed to evaluate the effectiveness of interventions in real-life routine practice conditions, whereas explanatory trials aim to test whether an ...
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Development and Validation of a Rapid Tool to Measure Pragmatic Abilities: The Brief Assessment of Pragmatic Abilities and Cognitive Substrates (APACS Brief)

open access: yesBehavioral Sciences
Pragmatics is key to communicating effectively, and its assessment in vulnerable populations is of paramount importance. Although tools exist for this purpose, they are often effortful and time-consuming, with complex scoring procedures, which hampers ...
Luca Bischetti   +15 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Pragmatics for argumentation

open access: yesJournal of Pragmatics, 2023
The relationship between argumentation and language has recently attracted a great deal of attention through various publications in the field of argumentation studies (see e.g., Boogaart et al., 2021; Hinton, 2021; Oswald et al., 2018; Oswald et al., 2020). In this paper I propose a historical overview of this relationship by narrowing the scope of my
openaire   +2 more sources

Home - About - Disclaimer - Privacy