Results 121 to 130 of about 276,479 (286)
Site‐Specific Enzymatic Syntheses of DNA Bearing Several Modifications From RNA or DNA Templates
Chemistry – A European Journal, EarlyView.A single‐tube protocol for enzymatic synthesis of DNA containing 1–3 site‐specific nucleobase modifications was developed based on repeated single nucleotide extension, primer extension, and exchange of template. ABSTRACT Two approaches for the enzymatic synthesis of DNA oligonucleotides (ONs) bearing multiple site‐specific modifications were explored.
Lukáš Kaiser +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
, 2019 Centrum Prahy je přetíženo komerčními aktivitami a dopravou, v jiných částech města se naopak těchto aktivit nedostává. Přeměna Prahy v polycentrické město se proto jeví jako klíčová pro její udržitelný rozvoj.
Anna Vinklárková
core
, 2020 Ideová studie revitalizace území pražského Výstaviště jako součásti veřejného prostoru parku Stromovka. V návaznosti na možný budoucí kontext lokality vzniká živé místo koncentrující kulturu, sport, vzdělání a občanskou vybavenost v kreativní městské ...
Eliška Martínková
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Beyond the Human Negotiator: Generative AI and the Threshold of Autonomous Decision‐Making
Conflict Resolution Quarterly, EarlyView.ABSTRACT This article provides a comprehensive framework for understanding the role of artificial intelligence (AI) in negotiation, evaluating contemporary systems through the specific case study of Large Language Models (LLMs). To address the lack of established terminology, it first proposes a new typology distinguishing Negotiation Supported by AI ...
Martin Svatos
wiley +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT Voluntary carbon offsetting programs (VCOPs) are available for airline passengers who want to take action and offset their scope 3 emissions. Yet, their uptake is very limited. In this study, we propose an integrated theoretical model involving the norm activation theory and protection motivation theory to understand airline passengers ...
Eric Tchouamou Njoya +4 more
wiley +1 more source
Family House in Prague 6 - Suchdol
, 2017 Rodinný dům PRAHA - SUCHDOL Obsahem této bakalářské práce je návrh rodinného domu v ulici U Bakalářů v městské části Praha 6 - Suchdol. Bydlení splňuje požadavky čtyřčlenné rodiny. Dům se nachází na mírně svažitém pozemku s dostatečně prostornou zahradní
Šimůnková Tereza
core +1 more source
The ESG Readiness Index Based on Lewin's Field Theory: The Case of the Czech Industrial Sector
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT The Corporate Sustainability Reporting Directive (CSRD) imposes comprehensive ESG data requirements, yet the literature predominantly evaluates ex‐post reporting quality rather than ex‐ante organizational readiness. Drawing on Kurt Lewin's Field Theory, this study develops and pilot‐tests an expert‐weighted ESG Readiness Index (ESGRI ...
Vojtěch Hlinák +5 more
wiley +1 more source