Results 131 to 140 of about 37,525 (284)

Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting

International Journal of Nanomedicine, 2018
Purpose Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs. However, their intestinal translocation to distal target sites and their implication in pharmacokinetic (PK)–pharmacodynamic
Rokaya Amara, A. Ramadan, Riham M. El-Moslemany, M. Eissa, M. El-Azzouni, L. El-Khordagui   +5 more
semanticscholar   +1 more source

Activity of praziquantel against Hymenolepis nana, at different development stages, in experimentally infected mice [PDF]

, 1984
Rubens Campos, Maria Cecília Reale Vieira Bressan, Marcilene Gomes Evangelista   +2 more
openalex   +1 more source

The COUNTDOWN Study Protocol for Expansion of Mass Drug Administration Strategies against Schistosomiasis and Soil-Transmitted Helminthiasis in Ghana

Tropical Medicine and Infectious Disease, 2018
(1) Background: Current international policy for schistosomiasis and soil-transmitted helminthiasis (STH) control emphasises mass administration of deworming drugs in school-based programmes.
Suzy J. Campbell, Mike Y. Osei-Atweneboana, Russell Stothard, Artemis Koukounari, Lucas Cunningham, Samuel K. Armoo, Nana-Kwadwo Biritwum, Margaret Gyapong, Eleanor MacPherson, Sally Theobald, Maame Esi Woode, Jahangir Khan, Louis Niessen, Emily R. Adams   +13 more
doaj   +1 more source

Artemether and Praziquantel: Origin, Mode of Action, Impact, and Suggested Application for Effective Control of Human Schistosomiasis

Tropical Medicine and Infectious Disease, 2018
The stumbling block for the continued, single-drug use of praziquantel (PZQ) against schistosomiasis is less justified by the risk of drug resistance than by the fact that this drug is inactive against juvenile parasites, which will mature and start egg ...
R. Bergquist, Hala Elmorshedy
semanticscholar   +1 more source

Praziquantel in the cerebrospinal fluid in neurocysticercosis

Arquivos de Neuro-Psiquiatria, 1985
In 10 patients with neurocysticercosis (NC), an assessment was made of the praziquantel (PZQ) concentration in the cerebrospinal fluid (CSF), in non-deproteinized serum and in protein-free serum: before administration of the drug and the 1st., 7th. and 21st. days of oral administration (50mg/kg/day during 21 days).
Spina-França, A., Machado, L. R., Nobrega, J. P. S., Livramento, J. A., Diekmann, H. W., Groll, E., Rezende, G. L. de   +6 more
openaire   +6 more sources

Praziquantel and clonorchiasis [PDF]

Antimicrobial Agents and Chemotherapy, 1987
S W Chapman, A C Lin
openaire   +2 more sources

Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial

Parasites & Vectors
Background Reliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance. Combination therapy targeting adult and juvenile schistosome worms is urgently needed to improve praziquantel ...
Charles O. Obonyo, Fredrick O. Rawago, Nicholas K. Makworo, Erick M. O. Muok   +3 more
doaj   +1 more source

Histopathological changes of the liver after praziquantel treatment in Clonorchis sinensis infected rabbits [PDF]

, 1987
Soon Hyung Lee, Sung‐Tae Hong, Chong Soon Kim, Woon Mok Sohn, Jong-Yil Chai, Yoon Seong Lee   +5 more
openalex   +1 more source

Cucurbita pepo Seed Oil Induces Microsatellite Instability and Tegumental Damage to Schistosoma mansoni Immature and Adult Worms In vitro

Infection and Drug Resistance, 2020
Amany Ibrahim Ammar, 1 Amira Fathy Afifi, 1 Abdallah Essa, 2, 3 Asmaa Galal-Khallaf, 4 Mostafa Mohamed Mokhtar, 5 Somaia Shehab-Eldeen, 2, 3 Amany Ahmed Rady 1 1Department of Medical Parasitology, Faculty of Medicine, Menoufia University, Shebin El Kom,
Ammar AI, Afifi AF, Essa A, Galal-Khallaf A, Mokhtar MM, Shehab-Eldeen S, Rady AA   +6 more
doaj  

Rapid detection of praziquantel using monoclonal antibody-based ic-ELISA and immunochromatographic strips

Food and Agricultural Immunology, 2019
Praziquantel (PZQ) is a broad-spectrum antiparasitic drug used in mammals and fish. In this study, we developed an indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) for the detection of PZQ residues.
Xinyi Shen, Liqiang Liu, Liguang Xu, Wei Ma, Xiaoling Wu, Gang Cui, Hua Kuang   +6 more
doaj   +1 more source