Results 131 to 140 of about 30,204 (224)

Comparative palatability of orally disintegrating tablets (ODTs) of Praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: A randomized, single-blind, crossover study

bioRxiv, 2019
Background Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the species of schistosome infecting humans; however, the current tablet formulation is not suitable for preschool age children mainly due to its ...
M. Mahende, E. Huber, E. Kourany-Lefoll, A. Ali, B. Hayward, D. Bezuidenhout, W. Bagchus, A. Kabanywanyi   +7 more
semanticscholar   +1 more source

Resolution of Praziquantel

PLoS Neglected Tropical Diseases, 2011
Praziquantel remains the drug of choice for the worldwide treatment and control of schistosomiasis. The drug is synthesized and administered as a racemate. Use of the pure active enantiomer would be desirable since the inactive enantiomer is associated with side effects and is responsible for the extremely bitter taste of the pill.We have identified ...
Michael Woelfle, Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer, Piero Olliaro, Matthew H Todd   +5 more
openaire   +4 more sources

Efficacy of a drug combination of praziquantel, pyrantel pamoate, and febantel against giardiasis in dogs [PDF]

, 1998
Stephen C. Barr, Dwight D. Bowman, Marguerite F. Frongillo, Steven L. Joseph   +3 more
openalex   +1 more source

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma. [PDF]

, 2019
Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Barboza, Mariana, Chamadol, Nittaya, Jamnongkan, Wassana, Khuntikeo, Narong, Lebrilla, Carlito B, Loilome, Watcharin, Pairojkul, Chawalit, Sithithaworn, Paiboon, Techasen, Anchalee, Thanan, Raynoo, Yongvanit, Puangrat   +10 more
core   +2 more sources

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies.
Cose, Stephen, Dunne, David W, Elliott, Alison M, Jones, Frances M, Kihembo, Macklyn, Mawa, Patrice A, Tweyongyere, Robert, Vennervald, Birgitte J, Webb, Emily L   +8 more
core   +5 more sources

Albendazole and Praziquantel: Review and Safety Monitoring in Korea

Infection & Chemotherapy, 2018
Albendazole (ADZ) and praziquantel (PZQT) have been used as anthelmintics for over 30 years. Worldwide, hundreds of millions tablets are administered to people and livestock every year.
Sung-Tae Hong
semanticscholar   +1 more source

Pharmacological and immunological effects of praziquantel against Schistosoma japonicum: a scoping review of experimental studies

Infectious Diseases of Poverty, 2018
BackgroundChemotherapy for schistosomiasis has been around for 100 years. During the past century, great efforts have been made to develop new antischistosomal drugs from antimonials to nonantimonials, and some of these have been used extensively in ...
S. Xiao, Jun Sun, Ming-gang Chen
semanticscholar   +1 more source

Complementary effect of Capparis spinosa L. and silymarin with/without praziquantel on mice experimentally infected with Schistosoma mansoni [PDF]

, 2018
Seham S. El‐Hawary, Kamilia F. Taha, F. N. Kirillos, Amal Abdo Dahab, Amira El-Mahis, Shaimaa H. El-Sayed   +5 more
openalex   +1 more source

A qualitative assessment of community perceptions and practices towards schistosomiasis prior to introduction of a potential novel treatment option for preschool-age children in Kenya

Frontiers in Tropical Diseases
BackgroundOver 50 million preschool-age children (PSAC) in Africa need treatment for schistosomiasis but are excluded due to lack of a suitable child-friendly medication. The Paediatric Praziquantel Consortium has developed a novel paediatric formulation
Janet Masaku, Janet Masaku, John M. Gachohi, John M. Gachohi, John M. Gachohi, Alice Sinkeet, Mary Maghanga, Florence Wakesho, Wyckliff Omondi, Lisa Sophie Reigl, Isabelle L. Lange, Isabelle L. Lange, Andrea S. Winkler, Andrea S. Winkler, Andrea S. Winkler, Sammy M. Njenga, Mary Amuyunzu-Nyamongo   +16 more
doaj   +1 more source

The COUNTDOWN Study Protocol for Expansion of Mass Drug Administration Strategies against Schistosomiasis and Soil-Transmitted Helminthiasis in Ghana

Tropical Medicine and Infectious Disease, 2018
(1) Background: Current international policy for schistosomiasis and soil-transmitted helminthiasis (STH) control emphasises mass administration of deworming drugs in school-based programmes.
Suzy J. Campbell, Mike Y. Osei-Atweneboana, Russell Stothard, Artemis Koukounari, Lucas Cunningham, Samuel K. Armoo, Nana-Kwadwo Biritwum, Margaret Gyapong, Eleanor MacPherson, Sally Theobald, Maame Esi Woode, Jahangir Khan, Louis Niessen, Emily R. Adams   +13 more
doaj   +1 more source