Results 151 to 160 of about 10,887,074 (251)

e-Assessment: past, present and future

, 2014
The goal of this paper is to provide an overview of the evolution of electronic assessment, or e-assessment, within the context of a developing e-pedagogy by investigating the changes occurring over time in the ways e-pedagogy is described.
Hench, Thomas
core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

2024 Assessment Seminar

Worksheet template and a sample of a completed worksheet that walks through the assessment cycle.
Byrne, Sephra
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Barriers and Priorities for Immunotherapy Implementation in Advanced Gastric Cancer: Findings from a Two-Phase Qualitative Study. [PDF]

J Gastrointest Cancer
Ragonese A, Airoldi M, Aquilano MC, Arborea G, Bencardino K, Castri F, De Vita F, Lotesoriere C, Panarese I, Pochettino P, Satolli MA, Strippoli A, Valentini A, Sciattella P, MAGIC Working Group.   +14 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Improving inter-rater reliability in radiographic edema scoring in acute respiratory failure through structured training and expert feedback. [PDF]

ATS Sch
Qurashi H, Jain P, Joyce R, Singh N, Inman K, Rizzo A, Gipson V, Sinopoli J, Mirza T, Ali R, Naghshtabrizi N, Bobrysheva H, Venkatesan N, Golubykh K, Prendergast N, Samanthapudi K, Maximous SI, Schaefer C, Hendricks A, Oliveria JP, Rabe C, Cluceru J, Negahdar M, McVerry BJ, Hughes E, Nouraie SM, Kitsios GD.   +26 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Paediatric Procedural Sedation and Analgesia in Emergency Departments: A Delphi Consensus Study. [PDF]

Emerg Med Australas
Cahís N, Sánchez-Manubens J, Baena I, Eslava A, Marín E, Ranera A, Velasco R, Corripio R.   +7 more
europepmc   +1 more source