Results 131 to 140 of about 27,476 (208)

ROOT-ExM: Super-Resolution Imaging of Proteins in <i>Arabidopsis</i> Roots by Expansion Microscopy. [PDF]

Bio Protoc
Shimizu Y, Maucort G, Fernández-Monreal M, Dumas F, Bayer EM, Boutté Y, Grison MS.   +6 more
europepmc   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Simulations predict improved valve performance without direct leaflet intervention after neonatal truncus arteriosus repair. [PDF]

J Thorac Cardiovasc Surg
Bornemann KM, Choi PS, Huber J, Reed AK, Sharir A, Maskatia SA, Marsden AL, Ma MR, Kaiser AD.   +8 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Influence of Piston Bowl Geometry and Hydrogen-Diesel Mixing Ratios on Dual-Fuel Engine Combustion. [PDF]

ACS Omega
Kumar R, Nath S, Atul, Ranjan V, Khan S, Ghoshal SK.   +5 more
europepmc   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics. [PDF]

Biomed Opt Express
Karnowski K, Milkiewicz J, Cetinkaya O, Pachacz A, Mączyńska-Walkowiak E, Młyniuk P, Curatolo A, Liżewski K, Abass A, Borycki D, Kałużny B, Marcos S, Elsheikh A, Grulkowski I, Wojtkowski M.   +14 more
europepmc   +1 more source

Engineering of Crystal and Domain Structures in Epitaxial Y:HfO2 Thin Films by YSZ Substrate Miscut

Advanced Science, EarlyView.
We investigate how YSZ substrate miscut influences crystal structure and domain formation in epitaxial Y‐doped HfO2 thin films. Using magnetron sputtering, high‐resolution X‐ray diffraction, atomic‐resolution scanning transmission electron microscopy, and first‐principles calculations, we systematically examine the characteristics of thickness‐ and ...
Jun Young Lee, Hyung‐Jin Choi, Kun Hee Ye, Haneul Choi, Byeong‐hyeon Lee, Min‐Seok Kim, Dong‐Hun Han, June Hyuk Lee, Sung Ok Won, Tae Heon Kim, Hye Jung Chang, Jung‐Hae Choi, Seung‐Hyub Baek   +12 more
wiley   +1 more source

Evaluation of bone formation within β-tricalcium phosphate scaffolds in a sheep scapular bioreactor model using micro-computed tomography analysis. [PDF]

Regen Biomater
Al Maruf DSA, Darnell M, Ren J, Tomaskovic-Crook E, Cheng K, Lewin W, Kruse HV, Lawrence D, Luo P, Wise IK, Gupta A, Leinkram D, Manzie T, Parthasarathi K, Wykes J, Low H, Froggatt C, McKenzie DR, Wallace G, Crook JM, Clark JR.   +20 more
europepmc   +1 more source