Results 201 to 210 of about 291,370 (256)

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi, Aleksander Luniewski, Vanessa Smith, Matthew McCord, Jaideep Kapur, Mark Quigg, Catherine Joshua, Ifrah Zawar   +7 more
wiley   +1 more source

Genomic evolution of SARS-CoV-2 delta variants pre- and post-omicron emergence using alignment-free machine learning models. [PDF]

PLoS One
Sankar S, Anandharaman K, Selvam P, Jayaraman A, Jayakumar D, Balakrishnan P, Larsson M, Velu V, Raju S, Shankar EM.   +9 more
europepmc   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Biogenic Silica Nanoparticles Enhance <i>Beauveria bassiana</i> Bioavailability and Efficacy for Sustainable Pest Control. [PDF]

ACS Omega
Harada LK, Guilger-Casagrande M, Germano-Costa T, Bilesky-José N, Polanczyk RA, Gonçalves KC, da Silva PG, Silva E Silva JV, Prado RM, Fraceto LF, Lima R.   +10 more
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Antimicrobial resistance emergence during war: looking for answers beyond antibiotics. [PDF]

Trauma Surg Acute Care Open
Kilgarriff S, Rock C.
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Molecular war and peace: the concurrent path to antibiosis and antibiotic resistance. [PDF]

Front Microbiol
Baquero F, Cantón R, Herencias C, Gama JA, Coque TM.   +4 more
europepmc   +1 more source

Phenology and parasitism rates of Xenos oxyodontes and Xenos moutoni (Strepsiptera: Xenidae) in Vespa (Hymenoptera: Vespidae) in South Korea. [PDF]

Parasite
Kim J, Kim CJ, Choi MB, Kwon O.
europepmc   +1 more source

Host oxidative stress primes mycobacteria for rapid antibiotic resistance evolution. [PDF]

Nat Commun
Pepper-Tunick E, Srinivas V, Mast FD, Li S, Russ S, Hanson W, Zamora AD, Wu WJ, Silcocks M, Thi Minh Ha D, Dunstan SJ, Nguyen Thuy Thuong T, Turkarslan S, Aitchison JD, Arrieta-Ortiz ML, Baliga NS.   +15 more
europepmc   +1 more source