Results 51 to 60 of about 290,834 (285)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pre-Emergence Rotting of Peas in South Australia [PDF]

open access: yesAustralian Journal of Biological Sciences, 1964
Pre-emergence rotting of peas by Pythium occurs during two stages of growth, namely when the radicle and plumule are breaking free of the testa and during elongation of the epicotyl prior to emergence.
NT Flentje, HK Saksena
openaire   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The Symptoms of Herbicidal Action: The Case of Aclonifen

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2015
The symptoms which were directly bound to the biochemical mode of action of an herbicide, other symptoms result from an indirect consequence of this action.
Özgür Kıvılcım Kılınç
doaj  

Formulation and Evaluation of Controlled-Release Diuron as Pre-Emergence Herbicide [PDF]

open access: yes, 1999
Controlled-release formulations of diuron were prepared in the laboratory using the concept of physical matrix utilizing sodium alginate and kaolin. The release rates of diuron from the formulations were determined by chemical assay and bioassay.
Mazlan, Norida
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Effect of Pre-sowing Treatments on Vegetative Growth and Production of Graftable Rootstocks in Mango

open access: yesInternational Journal of Bio-Resource and Stress Management, 2021
The present investigations “Studies on the effect of pre-sowing treatment and time of wedge grafting on production of saleable grafts in mango”were carried out in the nursery block of Fruit Science Department.
Sanjeev Kumar Banyal   +2 more
doaj  

Predicting species emergence in simulated complex pre-biotic networks. [PDF]

open access: yesPLoS ONE, 2018
An intriguing question in evolution is what would happen if one could "replay" life's tape. Here, we explore the following hypothesis: when replaying the tape, the details ("decorations") of the outcomes would vary but certain "invariants" might emerge ...
Omer Markovitch, Natalio Krasnogor
doaj   +1 more source

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