Results 71 to 80 of about 4,582,722 (288)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Early verb development in one croatian-speaking child [PDF]
This paper shows the early development of the first approximately 50 verbs found in the recorded speech production of one Croatian girl. The aim is to analyse and interpret the child's verb development in terms of the distinction of a pre- and a ...
Katičić, Antigone
core
Emergence of the primordial pre-60S from the 90S pre-ribosome. Ismail et al.
Original raw data from Ismail et al " Emergence of the primordial pre-60S from the 90S pre-ribosome"THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Ismail, S (via Mendeley Data) +1 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Chemical Control of the Invasive Weed Trianthema portulacastrum: Nethouse Studies
Trianthema portulacastrum L. (Aizoaceae), commonly known as desert horse purslane or black pigweed, is a C4 dicot succulent invasive annual plant that is widespread in agricultural fields in Southeast Asia, tropical America, Africa, and Australia.
Yaakov Goldwasser +5 more
doaj +1 more source
Possibilities of herbicide applications to the self-heal (Prunella vulgaris L.) growth were tested in 1997-1998. Experiments showed that the application of pre-emergence herbicides in the Prunella vulgaris L.
J. Neugebauerová, K. Petříková
doaj +1 more source
Behaviour of pre-emergence herbicides in poplar nurseries
The poplar cutting response to five pre-emergence herbicides (Oxadiazon, Isoxaben, Oxifluorfen, Tiazopir and Pendimetaline) in nursery conditions were studied. In order to evaluate quantitatively the selectivity and efficacy of the herbicides, the shoot height of the trees and the dry weight of the weeds were recorded. Species were identified and their
Sixto, H. +2 more
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

