Results 91 to 100 of about 291,370 (256)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Efficient Nitrogen Management for Reducing Weed Population and Improving Productivity of Boro Rice
Among many causes of weed growth and rice's low yield, improper nitrogen management are thought to be an important issue. An experiment was conducted from December 2021 to June 2022 at the Agronomy Field Laboratory, Bangladesh Agricultural ...
Md. Hasan Miah +5 more
doaj +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
A field experiment was conducted at Floricultural Research Station, Hyderabad, Telangana under irrigated conditions for three consecutive years from 2009−10 to 2011−12 on Chrysanthemum variety Mayuri with pre-emergence herbicides Butachlor ...
P. Lalitha Kameswari, A. Girwani
doaj
Seed Physiological Quality and Selectivity of Pre-Emergence Herbicides in Soybean (Glycine max L.)
Seed physiological quality significantly affects crop performance. Besides proper crop establishment, pre-emergence herbicides constitute one major weed-control strategy.
Alessandro Guerra da Silva +7 more
doaj +1 more source
Pre-emergence Oxygenation and Postoperative Atelectasis [PDF]
openaire +2 more sources
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

