Results 91 to 100 of about 12,962,114 (359)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Resuscitation with pre-hospital blood products in adults with trauma-related haemorrhagic shock: the RePHILL RCT

Efficacy and Mechanism Evaluation
Background The treatment of traumatic haemorrhagic shock has been transformed through better haemorrhage control, use of tranexamic acid and use of blood products.
Nicholas Crombie, Heidi A Doughty, Jonathan RB Bishop, Amisha Desai, Emily F Dixon, James M Hancox, Mike J Herbert, Caroline Leech, Simon J Lewis, Mark R Nash, David N Naumann, Karen Piper, Gemma Slinn, Hazel Smith, Iain M Smith, Rebekah K Wale, Alastair Wilson, Aisling Crombie, Mark Midwinter, Natalie Ives, Gavin D Perkins   +20 more
doaj   +1 more source

The success of pre-hospital tracheal intubation by different pre-hospital providers: a systematic literature review and meta-analysis

Critical Care, 2017
BackgroundPre-hospital basic airway interventions can be ineffective at providing adequate oxygenation and ventilation in some severely ill or injured patients, and advanced airway interventions are then required.
K. Crewdson, K. Crewdson, D. Lockey, D. Lockey, D. Lockey, J. Røislien, H. Lossius, H. Lossius, M. Rehn, M. Rehn, M. Rehn   +10 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Stress of nursing professionals working in pre-hospital care

Revista Brasileira de Enfermagem, 2020
Objectives: To analyze the factors related to the occupational stress of a Mobile Emergency Care Service (Samu) nursing team. Methods: This is a descriptive study, with a quantitative approach, performed with nursing professionals from Samu service of a ...
A. Carvalho, I. Frazão, D. Silva, M. S. Andrade, S. Vasconcelos, Jael Maria de Aquino   +5 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Variance Analysis of Expatriate Pre-Hospital Provider Training in Bahrain

Open Access Emergency Medicine, 2022
Moza M Alnoaimi,1,2 Alexander Hart,1,3 Fadi Issa,1,4 Attila Hertelendy,1,5 Amalia Voskanyan,1 Gregory Ciottone1,4 1Department of Emergency Medicine, Disaster Medicine Fellowship, Beth Israel Deaconess Medical Centre (BIDMC), Boston, MA, USA; 2Department ...
Alnoaimi MM, Hart A, Issa F, Hertelendy A, Voskanyan A, Ciottone G   +5 more
doaj  

Assessment of pre-hospital emergency medical services in low-income settings using a health systems approach

International Journal of Emergency Medicine, 2018
Emergency medical services (EMS) is defined as the system that organizes all aspects of care provided to patients in the pre-hospital or out-of-hospital environment.
A. Mehmood, Armaan A. Rowther, Olive C Kobusingye, A. Hyder   +3 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Iranian pre-hospital emergency care nurses' strategies to manage workplace violence: A descriptive qualitative study.

Journal of Nursing Management, 2019
AIM To explore the experiences of Iranian nurses working in pre-hospital emergency care services and the strategies used to manage of workplace violence.
Abbas Dadashzadeh, A. Rahmani, H. Hassankhani, M. Boyle, E. Mohammadi, S. Campbell   +5 more
semanticscholar   +1 more source