Results 21 to 30 of about 1,495,331 (245)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Designing a Mobile Device for Pre-hospital Care [PDF]
, 2013 Peer ...
Mellish, Christopher Stuart +5 more
core
Pre hospital care in Europe [PDF]
Emergency Medicine Journal, 2005 The delivery of prehospital care varies greatly across Europe, but the Hesculaep Project funded by the European Union aims to map the provision of prehospital care in the 25 countries of Europe. The Hesculaep1 Project funded by the European Union aims to map the provision of prehospital care in the 25 countries of Europe.
openaire +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Haemorrhage control of the pre-hospital trauma patient. [PDF]
, 2014 . This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
B Sorensen +5 more
core +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Developing new ways of measuring the impact of ambulance service care [PDF]
, 2014 Background Pre-hospital care in England is provided by ambulance services who deliver a diverse range of services to over 9 million patients a year but there is limited evidence about the effectiveness of this care.
Coster, Joanne +4 more
core
The use of segmented regression in analysing interrupted time series studies : an example in pre-hospital ambulance care [PDF]
, 2014 Peer reviewedPublisher ...
AK Wagner +13 more
core +2 more sources
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source