Results 91 to 100 of about 10,067,716 (258)

The top five research priorities in physician-provided pre-hospital critical care: a consensus report from a European research collaboration

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2011
Background Physician-manned emergency medical teams supplement other emergency medical services in some countries. These teams are often selectively deployed to patients who are considered likely to require critical care treatment in the pre-hospital ...
Lockey David, Fevang Espen, Thompson Julian, Lossius Hans   +3 more
doaj   +1 more source

Practice of Pre-Hospital Emergency Care and Associated Factors in Addis Ababa, Ethiopia: Facility-Based Cross-Sectional Study Design

, 2023
Azanaw Abebe, Zegeye Kebede, Dereje Bayissa Demissie Schools of Nursing, St. Paul’s Hospital Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Dereje Bayissa Demissie, School of Nursing, St.
Demissie DB, Abebe A, Kebede Z
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

CPR Quality Officer role to improve CPR quality: A multi-centred international simulation randomised control trial

Resuscitation Plus
Background: An out-of-hospital cardiac arrest requires early recognition, prompt and quality clinical interventions, and coordination between different clinicians to improve outcomes. Clinical team leaders and clinical teams have high levels of cognitive
Kacper Sumera, Tomasz Ilczak, Morten Bakkerud, Jon Dearnley Lane, Jeremy Pallas, Sandra Ortega Martorell, Agnieszka Sumera, Carl A. Webster, Tom Quinn, John Sandars, A. Niroshan Siriwardena   +10 more
doaj   +1 more source

PHECC clinical guidelines for pre-hospital emergency care: advanced paramedic

, 2012
This 2012 Edition offers current best practice guidance. The guidelines have expanded in number and scope – with 73 CPGs in total for Advanced Paramedics, covering such topics as Post Resuscitation Care for Paediatric patients and End of Life – DNR ...
King, Geoff, Dempsey, Pauline, Power, Brian, Egan, Jacqueline   +3 more
core  

Pre-hospital care for the anaesthetist

, 2017
Pre-hospital care is arguably the newest medical specialty having evolved from the introduction of portable defibrillators in the 1970s to the advanced critical care and interventions delivered today.
Nicholas Crombie, Bert Dercksen, G. Boukes Eindhoven   +2 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes

Emergency Medicine International, 2012
Introduction. Opioid overdose is an ever-increasing problem globally. Recent studies have demonstrated that intranasal (IN) naloxone is a safe and effective alternative to traditional routes of naloxone administration for reversal of opioid overdose ...
Cian McDermott, Niamh C. Collins
doaj   +1 more source

Determinants of pre-hospital care non-usage for patients with emergency care needs [including commentary by Snooks H.]\ud \ud

, 2000
Objective-To establish the demographic, health status and insurance determinants of pre-hospital ambulance non-usage for patients with emergency medical needs. \ud \ud Methods-Triage category, date of birth, sex, marital status, country of origin, method
FitzGerald, Gerard J., Purdie, J., Clark, Michele J.   +2 more
core  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source