Results 91 to 100 of about 240,689 (215)
Resuscitation PlusObjectives: With more elderly presenting with Out-of-Hospital Cardiac Arrests (OHCAs) globally, neurologically intact survival (NIS) should be the aim of resuscitation.
Chloe Alexis Ong +13 more
doaj +1 more source
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Advanced Science, EarlyView.Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li +21 more
wiley +1 more source
Pre-hospital emergency medicine and the trauma intensive care unit. [PDF]
J Intensive Care Soc, 2019 Frostick E, Johnson C.
europepmc +1 more source
Advanced Science, EarlyView.Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song +9 more
wiley +1 more source
Advanced Science, EarlyView.This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang +8 more
wiley +1 more source
A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
Advanced Science, EarlyView.This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Designing, implementation and evaluation of E-portfolio in pre-hospital emergency medical students and determining the users\' attitude [PDF]
مجله علمی دانشگاه علوم پزشکی کردستانBackground and Aim: The interest and attention of the new generation of students to electronic learning and the use of digital tools has increased, and the students of the field of pre-hospital emergency medicine also spend field internships in various ...
mehrnoosh Khoshnoodifar +4 more
doaj
Enhancing military airway suction devices with a focus on performance and portability
BMC Emergency MedicineBackground Airway management is critical in combat casualty care, with airway compromise being the second leading cause of preventable battlefield deaths.
Maria J. Londono +6 more
doaj +1 more source