Results 71 to 80 of about 6,517,332 (327)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Comparison of the short-term neonatal outcomes of preterm neonates before and after the launch of human milk bank in Iran: a retrospective descriptive study

open access: yesBMC Pediatrics
Background Preterm delivery continues to be a major concern in the global health system. Where accessible, mother’s milk is the optimal option for neonate nutrition.
Nazanin Hamidi   +4 more
doaj   +1 more source

Delamination failure analysis of G10 insulator in electromagnetic rail launcher

open access: yesHigh Voltage, 2023
The electromagnetic (EM) rail launcher G10 insulator is prone to delamination damage during launch, which affects the service life of the insulator. Through the secondary development of ABAQUS® commercial finite‐element software, an EM‐structure coupling
Xinkai Hu   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Planckpre-launch status: Low Frequency Instrument optics [PDF]

open access: yesAstronomy and Astrophysics, 2010
We describe the optical design and optimisation of the Low Frequency Instrument (LFI), one of two instruments onboard the Planck satellite, which will survey the cosmic microwave background with unprecedented accuracy. The LFI covers the 30-70 GHz frequency range with an array of cryogenic radiometers.
M Sandri   +18 more
openaire   +3 more sources

Financial Operational Losses in Space Launch [PDF]

open access: yes, 2017
The high cost of access to space has been a problem since the beginning of the space age. Most attempts to reduce this cost are centered on improvements to launch vehicle design.
Boone, Tom
core  

Effects of space flight on seed germination indices and some of its components [PDF]

open access: yesعلوم، فناوری و کاربردهای فضایی
Seed germination and seedling establishment are considered an essential growth stage and the first stage of plant adaptation in extraterrestrial environments.
Fateme Mousavi
doaj   +1 more source

Landsat-8 on-orbit and Landsat-9 pre-launch sensor radiometric characterization

open access: yesAsia-Pacific Remote Sensing, 2018
Landsat-8 has been operating on-orbit for 5+ years. Its two sensors, the Operational Land Imager (OLI) and Thermal Infrared Sensor (TIRS), are continuing to produce high quality data.
B. Markham   +9 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy