Results 151 to 160 of about 226,792 (352)
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
An Episode of Occultation Events in Gaia21bcv
The Astronomical JournalA previously unremarkable star near the Canis Major OB1/R1 association underwent an episode of multiple deep brightness minima. Light curves based on archival Gaia, Zwicky Transient Facility (ZTF), and NEOWISE data and additional observations from the ...
Klaus W. Hodapp +6 more
doaj +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Tests of Disk-locking in T Tauri Stars of the Orion Nebula Cluster
The Astrophysical JournalWe look for specific correlations predicted by magnetospheric accretion models for young stars that assume disk-locking using stellar and accretion parameters derived from low-resolution HST-STIS spectra of 33 T Tauri stars in the Orion Nebula Cluster ...
Margaret A. Mueller +3 more
doaj +1 more source
Rotation and stellar evolution
EPJ Web of Conferences, 2013 The effects of rotation on the evolution and properties of low-mass stars are first discussed from the pre-main sequence to the red giant phase. We then briefly indicate how some observational constraints available for these stars can help us progress in
Eggenberger P.
doaj +1 more source
Magnetic Activity of Pre-main Sequence Stars [PDF]
Symposium - International Astronomical Union, 2004 I review here recent advances in our understanding of magnetic activity in pre-main sequence (PMS) protostars and T Tauri stars. Results are based on recent imaging, spectroscopic and temporal studies of nearby star forming regions from the Chandra X — ray Observatory and XMM — Newton, including a first look at an ultradeep Chandra exposure of the ...
openaire +2 more sources
, 2015 Images obtained with the Gemini Multi-Object Spectrograph on Gemini South are used to examine the photometric properties and spatial distributions of main sequence (MS) and pre-main sequence (PMS) objects in the star cluster NGC 2401.
Davidge, T. J.
core +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source