Results 171 to 180 of about 241,576 (378)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The influence of the magnetic field orientation on the angular momentum loss in the pre-main sequence phase: The case of very slowly rotating magnetic Ap stars [PDF]

, 2002
K. Stȩpień, J. D. Landstreet
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

JWST Reveals Carbon-rich Chemistry in a Transitional Disk

The Astronomical Journal
We present JWST-MIRI Medium Resolution Spectrometer observations of the Classical T Tauri stars GM Aur and RX J1615.3-3255 (J1615), both hosting transitional disks.
M. Volz, C. C. Espaillat, C. V. Pittman, S. L. Grant, T. Thanathibodee, M. McClure, B. Tabone, N. Calvet, F. M. Walter   +8 more
doaj   +1 more source

VARIABILITY OF DISK EMISSION IN PRE-MAIN SEQUENCE AND RELATED STARS. II. VARIABILITY IN THE GAS AND DUST EMISSION OF THE HERBIG Fe STAR SAO 206462 [PDF]

, 2011
Michael L. Sitko, Amanda N. Day, Robin L. Kimes, Lori C. Beerman, Cameron Martus, David K. Lynch, Ray W. Russell, Carol A. Grady, Glenn Schneider, Carey M. Lisse, Joseph A. Nuth, Michel Curé, Arne A. Henden, Stefan Kraus, Veronica Motta, Motohide Tamura, Jeremy Hornbeck, Gerard M. Williger, Dino Fugazza   +18 more
openalex   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

An Episode of Occultation Events in Gaia21bcv

The Astronomical Journal
A previously unremarkable star near the Canis Major OB1/R1 association underwent an episode of multiple deep brightness minima. Light curves based on archival Gaia, Zwicky Transient Facility (ZTF), and NEOWISE data and additional observations from the ...
Klaus W. Hodapp, Eric Gaidos, Matthew A. Kenworthy, Michael Tucker, Benjamin J. Shappee, Anna V. Payne, Aaron Do   +6 more
doaj   +1 more source

Pulsations in pre-Main Sequence stars: The case of HD 34282 [PDF]

, 2004
P. J. Amado, A. Moya, J. C. Suárez, S. Martín‐Ruiz, R. Garrido, E. Rodrı́guez, C. Catala, M. J. Goupil   +7 more
openalex   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Tests of Disk-locking in T Tauri Stars of the Orion Nebula Cluster

The Astrophysical Journal
We look for specific correlations predicted by magnetospheric accretion models for young stars that assume disk-locking using stellar and accretion parameters derived from low-resolution HST-STIS spectra of 33 T Tauri stars in the Orion Nebula Cluster ...
Margaret A. Mueller, Christopher M. Johns-Krull, Keivan G. Stassun, Don M. Dixon   +3 more
doaj   +1 more source