Results 301 to 310 of about 270,676 (398)

LARD: A new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing

, 1997
Gavin Screaton, Xiao-Ning Xu, Anna L Olsen, Alison E. Cowper, Rusung Tan, Andrew J. McMichael, John I. Bell   +6 more
openalex   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration. [PDF]

Nucleic Acids Res
Yang WQ, Ge JY, Zhang X, Zhu WY, Lin L, Shi Y, Xu B, Liu RJ.   +7 more
europepmc   +1 more source

Phosphorylation Regulates In Vivo Interaction and Molecular Targeting of Serine/Arginine-rich Pre-mRNA Splicing Factors

, 1999
Joanne M. Yeakley, Hélène Tronchère, James Olesen, Jacqueline A. Dyck, Huan‐You Wang, Xiang‐Dong Fu   +5 more
openalex   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

Cell, 2012
Eric T. Wang, Neal A. L. Cody, Sonali P. Jog, M. Biancolella, Thomas T. Wang, D. Treacy, Shujun J Luo, G. Schroth, D. Housman, S. Reddy, Eric Lécuyer, C. Burge   +11 more
semanticscholar   +1 more source

Haplotype‐resolved genome and pan‐genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens

iMetaOmics, EarlyView.
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu, Chen Peng, Anhong Chen, Kaiyu Chen, Xinli Zheng, Dongyou Yu, Zhengguang Wang, Lingzhao Fang, George E. Liu, Pengju Zhao   +9 more
wiley   +1 more source

Modification of BCLX pre-mRNA splicing has antitumor efficacy alone or in combination with radiotherapy in human glioblastoma cells. [PDF]

Cell Death Dis
Dou Z, Lei H, Su W, Zhang T, Chen X, Yu B, Zhen X, Si J, Sun C, Zhang H, Di C.   +10 more
europepmc   +1 more source

Histone H3K36 methylation regulates pre-mRNA splicing in Saccharomyces cerevisiae

RNA Biology, 2016
M. Sorenson, D. Jha, Stefanie A Ucles, Danielle M Flood, B. Strahl, S. Stevens, Tracy L. Kress   +6 more
semanticscholar   +1 more source