Results 51 to 60 of about 1,309 (214)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Quantitative Reduction of Vowel Graph ‘a’ and ‘o’ Positioned after the Hard Consonants in the Speech of Native and Non-Native Russian Speakers in Lithuania

open access: yesRespectus Philologicus, 2015
This article analyses the absolute duration (ms) of stressed Russian vowels /a/, /o/ (graphs: “a”, “o”) and their allophones in unstressed positions after the hard consonants in the pronunciation of native and non-native Russian speakers in Lithuania ...
Danutė Balšaitytė, Vitalijus Kodzis
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modeling and design of a pre-stressed piezoelectric stack actuator

open access: yesAIP Advances, 2017
To provide a method for designing a pre-stressed PSA with high-performance, it is very meaningful to model the dynamic characteristics of the pre-stressed PSA accurately.
Shiping Jiang, Lei Cheng
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Technology of individual tensioning of strings in pre-stressed constructions – development and the implementation work [PDF]

open access: yesActa Montanistica Slovaca, 1998
The article, discussing the role of the pre-stressed and string concrete elements that are progressive in comparison with reinforced concrete constructions, contributes to the string concrete pre-tensioning technology development in Poland.
Aposto³ Marcin   +2 more
doaj  

Transverse deformation effect on sensitivity of strain-sensing patch antenna

open access: yesInternational Journal of Distributed Sensor Networks, 2020
The strain sensor based on microwave patch antenna is proposed to monitor structural strain in structural health monitoring. When patch antenna experiences deformation, the resonant frequency of patch antenna will shift.
Chunfeng Wan   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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