Results 41 to 50 of about 5,250 (307)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Precast Concrete Deck-to-Girder Connection using UHPC [PDF]
, 2019 The implementation of ultra-high-performance concrete (UHPC) in bridge construction has been growing rapidly in the last two decades due to its excellent mechanical properties, workability, and durability.
Abo El-Khier, Mostafa, Morcous, George
core +1 more source
Tissue Triage and Freezing for Models of Skeletal Muscle Disease [PDF]
, 2014 Skeletal muscle is a unique tissue because of its structure and function, which requires specific protocols for tissue collection to obtain optimal results from functional, cellular, molecular, and pathological evaluations.
Beggs, Alan H. +11 more
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Advances in the Hopkinson bar testing of irradiated/non-irradiated nuclear materials and large specimens [PDF]
, 2014 A brief review of the technological advances of the Hopkinson bar technique in tension for the study of irradiated/non-irradiated nuclear materials and the development of this technology for large specimens is presented.
ALBERTINI Carlo +2 more
core +1 more source
BuildingsPre-tensioned T-beams with polygonal tendons offer high load-bearing capacity and suitability for large spans, demonstrating broad application potential in bridge engineering.
Jinglin Tao +3 more
doaj +1 more source
Experimental study on internal monitoring structure of a new prestressed anchor cable
Yantu gongcheng xuebao, 2020 On account of their difficult internal stress monitoring, a new type of internal stress monitoring structure for pre-stressed anchor cables is developed and then tested by the destructive tension tests and the repeated tension tests under multi-levelload.
SUN Yan-peng 1, 2, LING Yong-yu 2, LIN Xing-chao 2, ZHAO Yu-fei 2, AN Xin-zan 2, YIN Tao 2
doaj +1 more source
Applied Sciences, 2022 Development of U-type pre-stressed girders has been attempted to increase the length of I-type girders in South Korea. However, a length of 30 m or less is common because the self-weight, according to the post-tension method, is large. In this study, the
Dong-Woo Seo +4 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.This study examines how several molten high‐silicon electrical steels interact with both conventional and recycled MgO–C refractories. For this, various immersion experiments are conducted. In addition to infiltration, a number of mechanisms are identified and explained that control the corrosion of the refractory material.
Lukas Neubert +7 more
wiley +1 more source