Results 151 to 160 of about 14,202,265 (305)

Pre-treatment prediction of microsatellite instability in colon cancer: a nomogram model combining clinicopathological features and pre-treatment CT-based radiomics. [PDF]

BMC Med Imaging
Wei M, Jia C, Zhang Y, You P, Chen W.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Pre-Hospital Emergency Care Council annual report 2009

, 2010
The Pre-Hospital Emergency Care Council (PHECC) is an independent statutory agency charged with responsibility for standards, education and training in pre-hospital emergency care in Ireland.
The Pre-Hospital Emergency Care Council (PHECC)
core  

Serum albumin, NLR and PLR in pre-treatment assessment of bronchiectasis exacerbations. [PDF]

Bioinformation
G R, Viswanathan VK.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Pharmacological treatment of pre-eclampsia

, 2018
Pre-eclampsia is characterized by sudden onset of high blood pressure during pregnancy, where the previous mother’s blood pressure was normal. If left untreated, pre-eclampsia causes serious complications.
Le, Tran Dang Khoa
core  

Pre-treatment cognitive impairment in patients with NSCLC: Prevalence and psychosocial factors. [PDF]

IBRO Neurosci Rep
Capetti B, Conti L, Luisi J, Sdinami S, Marzorati C, Grasso R, Frassoni S, Bagnardi V, Chiari M, Casiraghi M, Pravettoni G.   +10 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluating the Prognostic Relevance of Pre-Treatment Epstein-Barr Virus Levels in Non-Endemic Pediatric Nasopharyngeal Carcinoma. [PDF]

Cancers (Basel)
Farrag A, Yang Y, Piao J, Younis L, Wagner HJ, Christiansen H, Römer T, Poore A, Szot C, Thibeau N, Yom SS, Pinsky BA, Le QT, Kamihara J, Ting DT, Laetsch TW, Chen KS, Rodriguez-Galindo C, Hayden RT, Kontny U, Gartrell RD.   +20 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source