Results 51 to 60 of about 2,517,213 (249)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Lignin-Containing Cellulose Nanomaterials: A Promising New Nanomaterial for Numerous Applications

Journal of Bioresources and Bioproducts, 2019
The demand for sustainable functional materials with an eco-friendly preparation process is on the rise. Lignocellulosics has been attributed as the most sustainable bioresource on earth which can meet the stringent requirements of functionalization ...
Chinomso M. Ewulonu, Xuran Liu, Min Wu, Huang Yong   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Hydrothermal pre-treatment of rapeseed straw

Bioresource Technology, 2010
As a first step for ethanol production from alternative raw materials, rapeseed straw was studied for fermentable sugar production. Liquid hot water was used as a pre-treatment method and the influence of the main pre-treatment variables was assessed. Experimental design and response surface methodology were applied using pre-treatment temperature and ...
Díaz Villanueva, Manuel Jesús, Cara-Corpas, Cristobal, Ruiz-Ramos, Encarnación, Romero-Pulido, Inmaculada, Moya, Manuel, Castro, Eulogio   +5 more
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Evaluasi Proses Pre-Treatment Sampah In PLTSa Bantargebang (Studi Kasus Pre-Treatment di PLTSa Bantargebang)

Jurnal Rekayasa Lingkungan, 2021
Pembangkit Listrik Tenaga Sampah (PLTSa) Bantargebang sudah memiliki unit pre-treatment sampah, namun kinerjanya masih belum sesuai harapan. Penelitian ini akan mengevaluasi dan memperbaiki metode pre-treatment yang ada agar dapat bekerja lebih optimal sebagai acuan proses pre-treatment sampah umpan PLTSa.
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Optimization of Pre-Treatment Process Parameters to Generate Biodiesel from Microalga

Energies, 2018
Cell disruption is an integral part of microalga production process, which improves the release of intracellular products that are essential for biofuel production.
Chukwuma Onumaegbu, Abed Alaswad, Cristina Rodriguez, Abdul G. Olabi   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Effects of Lactic Acid and Ascorbic Acid Mixture on Quality Properties of Wild Red Deer (Cervus elaphus) Meat

Applied Sciences
This study investigated the effect of a 2% lactic acid and 2% ascorbic acid mixture, applied via a spray method, on the quality of wild red deer (Cervus elaphus) meat stored under vacuum packaging at 4 ± 1 °C for 21 days.
Munkhnasan Enkhbold, Attila Lőrincz, Majd Elayan, László Friedrich, Annamária Barkó, Tamás Csurka, Anikó Boros, Géza Hitka, Adrienn Varga-Tóth   +8 more
doaj   +1 more source