Results 171 to 180 of about 1,386,765 (307)

Impact of Virtual Reality Headset on Pain and Anxiety for Bedside Abdominal VAC Dressing Change (VIRPA): A Randomized Controlled Clinical Trial. [PDF]

Health Sci Rep
Barberá-Carbonell B, Kefleyesus A, Djafarrian R, Geinoz S, Hahnloser D, Grass F, Hübner M.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Investigation of varenicline and tropisetron in latent inhibition and novel object recognition in mice. [PDF]

Sci Rep
Lizarraga-Valderrama LR, Williams S, Watson DJG, Granger KT, Gibson CL, Moran PM.   +5 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

TAX EVASION: INITIATION OF PRE-TRIAL INVESTIGATION, PRIORITY ACTIONS, FOCUS AREAS OF THE PRE-TRIAL INVESTIGATION BODY

Law Bulletin, 2023
openaire   +1 more source

PACE-NODES: A phase III randomised trial of 5 fraction prostate stereotactic body radiotherapy (SBRT) versus 5 fraction prostate and pelvic nodal SBRT. [PDF]

Clin Transl Radiat Oncol
Pathmanathan A, Jain S, Staffurth J, Brown S, Burnett S, Cafferty FH, Choudhury A, Dewan M, Hoskin P, McBride K, McGarry CK, Miles E, Murray J, Murthy V, Naismith O, Song YP, Syndikus I, Tree A, Ward T, Hall E, van As N.   +20 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

The effect of LysaKare infusion on serum potassium levels in patients with gastroenteropancreatic neuroendocrine tumours eligible for treatment with [¹⁷⁷Lu]Lu-DOTA-TATE: A post-authorisation safety study. [PDF]

J Neuroendocrinol
Hofland J, Grana CM, Weickert MO, Moore AR, Shah T, Prakash V, Kolasińska-Ćwikła A, de Herder WW, Spada F, Xu L, Fite R, Wu Y, Ćwikła JB.   +12 more
europepmc   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Probiotic supplementation for anxiety symptoms in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial. [PDF]

NPJ Parkinsons Dis
Lam JST, Tosefsky KN, Ainsworth NJ, Meng D, Uzelman P, Zhu J, Cirstea MS, Pio F, Vila-Rodriguez F, Howard AK, Finlay BB, Appel-Cresswell S.   +11 more
europepmc   +1 more source