Results 101 to 110 of about 147,586 (226)

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source

Individual 17-Hydroxyprogesterone Responses to hCG Are Not Correlated With Follicle Size in Polycystic Ovary Syndrome. [PDF]

, 2019
Context:In women with polycystic ovary syndrome (PCOS), 17-hydroxyprogesterone (17-OHP) responses to gonadotropin stimulation vary from increased to indistinguishable compared with normal controls.
Chang, R Jeffrey, Duleba, Antoni J, Garzo, Gabriel, Homer, Michael V, Lawson, Mark A, Toloubeydokhti, Tannaz   +5 more
core   +1 more source

The Impact of Melatonin Supplementation on Various Aspects of Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Polycystic ovary syndrome (PCOS) is a prevalent gynecological condition affecting women of reproductive age, with implications for multiple aspects of women's health. Recent research indicates that melatonin (MLT) may enhance several dimensions of this syndrome via various mechanisms. Consequently, this study was undertaken
Seyedeh Shahed Shoarishoar, Zainab Alimoradi, Fatemeh Alsadat Rahnemaei, Saeed Mehrzadi, Fatemeh Abdi   +4 more
wiley   +1 more source

Razvoj in vitro preantralnih folikula u uzgoju s kumulusnim ili granuloznim stanicama. [PDF]

, 2010
Low reproductive effifi ciency in buffalo limits the number of offspring produced during lifespan and thus results in under-exploitation of the superior female genetic material.
Bodhaganahalli M. Manjunatha, Hondaravalli S. Ramesh, Paluru S. P. Gupta, Sumanta Nandi   +3 more
core   +1 more source

Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism [PDF]

, 2016
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis.
Abruzzese, Giselle Adriana, Ferreira, Silvana Rocío, Heber, María Florencia, Motta, Alicia Beatriz, Pignataro, Omar Pedro, Reynoso, Roxana María, Velez, Leandro Martin   +6 more
core   +2 more sources

Impact of Neutral Sphingomyelinase Inhibition on Small Extracellular Vesicle Production by Mural Granulosa Cells and In Vitro Folliculogenesis in Mice

Molecular Reproduction and Development, Volume 92, Issue 10, October 2025.
ABSTRACT Small extracellular vesicles (sEVs) function as critical regulators of ovarian follicular development. Although several pathways, including one involving neutral sphingomyelinase (nSMase), contribute to sEV production, the specific pathway active in ovarian follicles has not been clearly identified.
Kodai Matsushita, Yuta Matsuno, Kazuma Kita, Ayaka Ichikawa, Natsumi Maruyama, Wataru Fujii, Tsutomu Endo, Koji Sugiura   +7 more
wiley   +1 more source

DTPA disrupts development of preantral ovarian follicles in vitro

Reproduction and Fertility
Dietary zinc deficiency disrupts fertility in vivo by impairing oocyte and embryo development near ovulation. Acute treatment of newborn ovaries with a strong intracellular chelator (TPEN), which preferentially binds zinc, disrupts follicular development.
James M Hester, Francisco J Diaz
doaj   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

Vitrification affects the expression of matrix metalloproteinases and their tissue inhibitors of mouse ovarian tissue

Iranian Journal of Reproductive Medicine, 2016
Background: One of the most major obstacles of ovarian tissue vitrification is suboptimal developmental competence of follicles. Matrix metalloproteinases 2 (MMP-2) and 9 (MMP-9) and their tissue inhibitors TIMP-1 and TIMP-2 are involved in the ...
Reza Asadzadeh, Shima Khosravi, Saeed Zavareh, Mohammad Taghi Ghorbanian, Seyed Hassan Paylakhi, Seyed Reza Mohebbi   +5 more
doaj  

In vitro development of bovine preantral follicles in monolayer of ovarian cells [PDF]

, 2001
O presente trabalho teve como objetivos determinar a influência de células ovarianas no desenvolvimento in vitro de folículos pré-antrais, avaliar a viabilidade das células ovarianas em monocamada e a influência do soro na manutenção de folículos pré ...
Carámbula, Silvia Ferreira, Costa, Luís Fabiano Santos da, Figueiredo, José Ricardo de, Gonçalves, Paulo Bayard Dias, Montagner, Marcelo Marcos, Neves, Jairo Pereira   +5 more
core   +2 more sources