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The prebiotic chemistry of nucleotides

Origins of Life, 1984
Diiminosuccinonitrile (DISN), formed by the oxidation of diaminomaleonitrile (DAMN), has been investigated as a potential prebiotic phosphorylating agent. DISN effects the cyclization of 3'-adenosine monophosphate to adenosine 2', 3'-cyclic phosphate in up to 39% yield. The mechanism of this reaction was investigated.
William J. Hagan   +2 more
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Thermodynamics of Prebiotic Phosphorylation

Chemical Reviews, 2019
The formation of organophosphate molecules by prebiotic processes relies on nonenzymatic synthesis. Given the centrality of phosphorylated biomolecules in metabolic, structural, and replicative processes, it is highly likely that such nonenzymatic synthesis had to occur early in Earth's history.
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An overview of probiotics and prebiotics

Nursing Standard, 2007
This article reviews the origins and background of probiotics. Evidence for the potential mechanisms of probiotics and prebiotics, and their interactions with the gastrointestinal tract and the immune system are discussed. Evidence is examined for the use of probiotics to treat infantile diarrhoea, irritable bowel syndrome, inflammatory bowel disease ...
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Prebiotics in obesity.

Panminerva medica, 2015
Obesity was probably rare in ancient times, with the current increase starting in the Industrial Revolution of the eighteenth century, and becoming much more widespread from about 1950, so concurrent with the increased consumption of carbohydrates from cereals in the Green Revolution.
Carnahan, Sharyn   +3 more
openaire   +1 more source

Dietary Fiber and Prebiotics

2014
Dietary fiber and prebiotics exert a great impact on health-promoting food for mankind. Under this aspect a general overview is given about the bioavailability of carbohydrates and their influence on dietary fiber intake and about the developing of the prebiotic concept and specific functional foods. Moreover, the occurrence and chemical composition of
Renate Loeppert   +4 more
openaire   +2 more sources

Prebiotic Peptides

2006
Based on modern geochemistry's view of the atmospheric and geological conditions on the primordial Earth ∼3.8–4 billion years ago, the most realistic scenario for the formation of amino acids and peptides in chemical evolution is discussed, including possible reasons for sequence preferences in early proteins and for biohomochirality.
Bernd M. Rode, Kristof Plankensteiner
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Prebiotics | Functions

2002
T. Sako, R. Tanaka
openaire   +1 more source

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