Results 131 to 140 of about 2,435,105 (382)

Higher probability of compound flooding from precipitation and storm surge in Europe under anthropogenic climate change

Science Advances, 2019
More intense precipitation will increase the flood potential from concurring storm surges and precipitation in the future. In low-lying coastal areas, the co-occurrence of high sea level and precipitation resulting in large runoff may cause compound ...
E. Bevacqua, D. Maraun, M. Vousdoukas, E. Voukouvalas, Mathieu Vrac, L. Mentaschi, M. Widmann   +6 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Uncertainty quantification of satellite precipitation estimation and Monte Carlo assessment of the error propagation into hydrologic response [PDF]

, 2006
The aim of this paper is to foster the development of an end-to-end uncertainty analysis framework that can quantify satellite-based precipitation estimation error characteristics and to assess the influence of the error propagation into hydrological ...
Hong, Y, Hsu, KL, Moradkhani, H, Sorooshian, S   +3 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Bias adjustment of satellite-based precipitation estimation using artificial neural networks-cloud classification system over Saudi Arabia [PDF]

, 2018
Precipitation is a key input variable for hydrological and climate studies. Rain gauges can provide reliable precipitation measurements at a point of observations.
Alharbi, R, Hsu, K, Sorooshian, S
core   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao, Zhuoma Danzhen, Yao Li, Junyu Zhu, Lan Chu, Zhang Yang   +5 more
wiley   +1 more source

The Importance of Humidity in the Afternoon Local-Scale Precipitation Intensity over Eastern China and Its Impacts on the Aerosol Effects

Remote Sensing
Thermally driven local-scale precipitation (LSP) is an important type of summer precipitation over China, but the prestorm environmental conditions remain unclear.
Xinlei Tang, Qian Chen, Jianping Guo, Jing Yang, Zeyong Zou, Jinghua Chen, Yue Sun   +6 more
doaj   +1 more source

Moyamoya Disease and the Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo, Jeong‐Yong Shin, Rugyeom Lee, Jiwon Cheon, Ji Hun Kim, Doeun Kim, Jae‐Kyung Won, In‐Hwan Oh, Yunjong Lee, Tae‐Beom Ahn   +9 more
wiley   +1 more source

On precipitation of metastable centres in solid solutions NaCl–CaCl2 [PDF]

, 1954
Susumu Miyake, Koji Suzuki
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source