Results 161 to 170 of about 17,403 (263)

Potential Impacts of Radio Frequency Interference on precipitation retrievals from space – from an IPWG perspective

, 2022
Chris Kidd, Philippe Chambon, Viviana Maggioni, Chris Kummerow, Joe Turk, I Strangeways, I Strangeways, C Kidd, G Huffman, A Becker, G Skofronick-Jackson, D Kirschbaum, P Joe, C Muller, C Kidd, G Huffman, V Maggioni, P Chambon, R Oki, K Imaoka, Coauthors, M Sapiano, W Berg, D Mckague, C Kummerow, D Draper, D Newell, Christian Kummerow, L David, Mark Randel, Nai-Yu Kulie, Ralph Wang, S Ferraro, Veljko Munchak, Petkovic, C Kummerow   +35 more
openalex   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Evaluating multi-source precipitation data for streamflow simulation using the SWAT model in the Alpine Manas River Basin, Northwest China. [PDF]

Sci Rep
Tan L, Zan C, Liu T, Xiong J, Zhang A.
europepmc   +1 more source

Deep Learning for Multi-Satellite Precipitation Retrievals: Impact of Tomorrow.io's Microwave Sounders

Forest Cannon, Simon Pfreundschuh, Brandon Taylor, S. Joseph Munchak, Ethan Nelson, J. L’Heureux, C. Owens, Luke Conibear, Stylianos Flampouris, Arun Chawla   +9 more
openalex   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

Advanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John, David M. Paganin, Marie‐Christine Zdora, Lisa Marie Petzold, Patrick Ilg, Junan Chen, Sara Baggio, Johannes B. Thalhammer, Sami Wirtensohn, Julian Moosmann, Jörg U. Hammel, Felix Beckmann, Samantha J. Alloo, Jannis N. Ahlers, Madleen Busse, Julia Herzen, Kaye S. Morgan   +16 more
wiley   +1 more source

Impact of Wind on Rainfall Measurements Obtained from the OTT Parsivel² Disdrometer. [PDF]

Sensors (Basel)
Chinchella E, Cauteruccio A, Lanza LG.
europepmc   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Wind shear enhances soil moisture influence on rapid thunderstorm growth. [PDF]

Nature
Taylor CM, Klein C, Barton EJ, Hahn S, Wagner W.   +4 more
europepmc   +1 more source

Spectra of high energy electron precipitation and atmospheric ionization rates retrieval from balloon measurements

, 2019
Irina Mironova, G. A. Bazilevskaya, G. A. Kovaltsov, A. A. Artamonov, Eugene Rozanov, Alexander Mishev, В. С. Махмутов, Arseniy Karagodin, Kseniia Golubenko   +8 more
openalex   +2 more sources

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source