Results 171 to 180 of about 17,403 (263)

Spatiotemporal mapping of alloy mesostructure dynamics via multimodal coherent X-ray diffraction imaging. [PDF]

Proc Natl Acad Sci U S A
Takazawa S, Ninomiya K, Ha MQ, Vu TS, Sasaki Y, Abe M, Uematsu H, Okawa N, Ishiguro N, Ozaki K, Hatsui T, Hoshino T, Nishibori M, Dam HC, Takahashi Y.   +14 more
europepmc   +1 more source

A prototype precipitation retrieval algorithm over land using passive microwave observations stratified by surface condition and precipitation vertical structure [PDF]

, 2015
Yalei You, Nai‐Yu Wang, Ralph Ferraro
openalex   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Fusion of multi-source precipitation records via coordinate-based generative models. [PDF]

Nat Commun
Sun S, Nai C, Pan B, Li W, Li L, Li X, Foufoula-Georgiou E, Lin Y.   +7 more
europepmc   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

From Swath to Full-Disc: Advancing Precipitation Retrieval with Multimodal Knowledge Expansion [PDF]

Zheng Wang, Kai Ying, Bin Xu, Chunjiao Wang, Cong Bai   +4 more
openalex   +1 more source

TRMM Common Microphysics Products: A Tool for Evaluating Spaceborne Precipitation Retrieval Algorithms [PDF]

, 2004
David E. Kingsmill, Sandra E. Yuter, Andrew J. Heymsfield, Peter V. Hobbs, Alexei Korolev, Stith Jeffrey L, Aaron Bansemer, Julie Haggerty, Arthur L. Rangno   +8 more
openalex   +1 more source

Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression

Advanced Science, EarlyView.
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng, Shuang Cai, Chen Guo, Shaker Khan, Lefan Liu, Qiong Tian, Zhiyuan Ma, Jian Zhang, Lingyu Zhao   +8 more
wiley   +1 more source

From observation to protection a bibliometric analysis of aerosol-glacier interactions. [PDF]

iScience
Meng H, Wang F, Liu S, Jin X, Xu M, Mu J.   +5 more
europepmc   +1 more source

Shrunken Locally Linear Embedding for Passive Microwave Retrieval of Precipitation [PDF]

, 2015
Ardeshir M. Ebtehaj, Rafael L. Bras, Efi Foufoula-Georgiou   +2 more
openalex   +1 more source