Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Generating high accuracy multi-layer soil moisture at daily scale in the black soil region of China. [PDF]
Chen L +9 more
europepmc +1 more source
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source
A dataset of carbon parameters for the 24,366 lakes in China from 40-year Landsat observations. [PDF]
Yan N +5 more
europepmc +1 more source
GSMaP Passive Microwave Precipitation Retrieval Algorithm : Algorithm Description and Validation
Kazumasa Aonashi +10 more
openalex +2 more sources
Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo +6 more
wiley +1 more source
An Improved SBAS-InSAR Processing Method Considering Phase Consistency: Application to Landslide Monitoring in Hualong County, Qinghai Province, China. [PDF]
Luo W +8 more
europepmc +1 more source
A Cs-Transunet-Based Precipitation Retrieval Algorithm with Spatial and Channel Information
Yanfang Lv +3 more
openalex +1 more source
Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
wiley +1 more source
SMCR: A first satellite-derived all-weather daily/1-km Soil Moisture Climatological Record (1980-2023). [PDF]
Zhai S +8 more
europepmc +1 more source

