Results 51 to 60 of about 2,510,789 (285)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

First In-orbit Experience of TerraSAR-X Flight Dynamics Operations [PDF]

open access: yes, 2007
TerraSAR-X is an advanced synthetic aperture radar satellite system for scientific and commercial applications that is realized in a public-private partnership between the German Aerospace Center (DLR) and the Astrium GmbH.
Kiehling, Reinhard   +11 more
core  

Precise Orbit Determination of Mars-crossing Asteroids

open access: yesThe Astronomical Journal
This study investigates the orbit determination of the Mars-crossing asteroids (MCAs) with a focus on the possibility of detecting their Yarkovsky signals. We analyze the influences of force model uncertainties on MCA orbits, including the uncertainty of
Xin Liu   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Two-Site Optical Observation and Initial Orbit Determination for Geostationary Earth Orbit Satellites [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2010
Optical observation system provides angle-only measurement for orbit determination of space object. Range measurement can be directly acquired using laser ranging or tone ranging system.
Jin Choi   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

OPERATIONAL ASPECTS OF ORBIT DETERMINATION WITH GPS FOR SMALL SATELLITES WITH A SAR PAYLOAD. [PDF]

open access: yes, 2005
Scientific small satellite missions for remote sensing with Synthetic Aperture Radar (SAR) payloads or high accuracy optical sensors, pose very strict requirements on the accuracy of the reconstructed satellite positions, velocities and accelerations ...
Zehetbauer, Tino   +2 more
core  

Real-Time Multi-GNSS Precise Orbit Determination Based on the Hourly Updated Ultra-Rapid Orbit Prediction Method

open access: yesRemote Sensing, 2022
Offering real-time precise point positioning (PPP) services for global and large areas based on global navigation satellite systems (GNSS) has drawn more and more attention from institutions and companies. A precise and reliable satellite orbit is a core
Bingfeng Tan   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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