Results 171 to 180 of about 850,443 (319)

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1029-1053, April 2025.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

High-precision surgical navigation using speckle structured light-based thoracoabdominal puncture robot [PDF]

open access: yesarXiv
Abstract Background During percutaneous puncture robotic surgical navigation, the needle insertion point is positioned on the patient's chest and abdomen body surface. By locating any point on the soft skin tissue, it is difficult to apply the traditional reflective ball tracking method.
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Multi-GNSS Precise Point Positioning Software Architecture and Analysis of GLONASS Pseudorange Biases [PDF]

open access: yes, 2015
With expanding satellite-based navigation systems, multi-Global Navigation Satellite System (GNSS) Precise Point Positioning (PPP) presents an advantage over a single navigation system, which improves position accuracy and enhances availability of ...
Aggrey, John Egyir
core  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Fixed points of DT transformations, cluster exponents and degrees of Weyl groups [PDF]

open access: yesarXiv
Inspired by a recent work of Y. Mizuno, we show that the DT transformations on a cluster ensemble of finite type admit unique totally positive fixed points, and that the exponents of the linearizations of the DT transformations at the fixed points are precisely the degrees of the Weyl group of the corresponding finite root system.
arxiv  

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

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