Results 121 to 130 of about 549,143 (317)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Fundamentals Models Versus Random Walk: Evidence From an Emerging Economy

open access: yesJournal of Forecasting, EarlyView.
ABSTRACT We analyze the predictive power of fundamentals versus random walk models for horizons from 1 to 24 months in an emerging market. Specifically, we investigate what fundamentals models outperform random walk during periods of appreciation and depreciation of the exchange rate.
Helder Ferreira de Mendonça   +2 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

open access: yesAdvanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li   +13 more
wiley   +1 more source

Characterizing Spatial Patterns of Base Stations in Cellular Networks [PDF]

open access: yesarXiv, 2014
The topology of base stations (BSs) in cellular networks, serving as a basis of networking performance analysis, is considered to be obviously distinctive with the traditional hexagonal grid or square lattice model, thus stimulating a fundamental rethinking.
arxiv  

Tightly coupled multi-frequency PPP-RTK/INS integration model and its application in an urban environment

open access: yesGeo-spatial Information Science
The Precise Point Positioning-Real Time Kinematic (PPP-RTK) technique, which provides centimeter-level positioning with instantaneous ambiguity resolution, is considered as a potential tool for intelligent vehicle applications.
Hang Zhu   +3 more
doaj   +1 more source

Intracell Interference Characterization and Cluster Inference for D2D Communication [PDF]

open access: yesarXiv, 2016
The homogeneous poisson point process (PPP) is widely used to model temporal, spatial or both topologies of base stations (BSs) and mobile terminals (MTs). However, negative spatial correlation in BSs, due to strategical deployments, and positive spatial correlations in MTs, due to homophilic relations, cannot be captured by homogeneous spatial PPP ...
arxiv  

Precise Point Positioning with the BeiDou Navigation Satellite System

open access: yesSensors, 2014
By the end of 2012, China had launched 16 BeiDou-2 navigation satellites that include six GEOs, five IGSOs and five MEOs. This has provided initial navigation and precise pointing services ability in the Asia-Pacific regions.
Min Li   +5 more
doaj   +1 more source

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