Results 81 to 90 of about 526,359 (299)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evaluation of Ionospheric Delay Effects on Multi-GNSS Positioning Performance
Ionospheric delay is a significant error source in multi-GNSS positioning. We present different processing strategies to fully exploit the ionospheric delay effects on multi-frequency and multi-GNSS positioning performance, including standard point ...
Ke Su, Shuanggen Jin, M. M. Hoque
doaj +1 more source
Model-based vs. model-free visual servoing: A Performance evaluation in microsystems [PDF]
In this paper, model-based and model-free image based visual servoing (VS) approaches are implemented on a microassembly workstation, and their regulation and tracking performances are evaluated.
Bilen, Hakan +6 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The emergence of multiple global navigation satellite systems (multi-GNSS), including global positioning system (GPS), global navigation satellite system (GLONASS), Beidou navigation satellite system (BDS), and Galileo, brings not only great ...
Wenju Fu +6 more
doaj +1 more source
High precision applications of the global positioning system [PDF]
The Global Positioning System (GPS) is a constellation of U.S. defense navigation satellites which can be used for military and civilian positioning applications.
Lichten, Stephen M.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This article aims to examine the real-time precise point positioning (PPP) solution’s accuracy utilizing the low-cost dual-frequency multi-constellation U-blox ZED-F9P module and real-time GNSS orbit and clock products from five analysis centers ...
Mohamed Abdelazeem +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

