CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo +15 more
wiley +1 more source
Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley +1 more source
A technical survey on practical applications and guidelines for IoT sensors in precision agriculture and viticulture. [PDF]
Pascoal D +5 more
europepmc +1 more source
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source
An adaptive hexagonal deployment model for resilient wireless sensor networks in precision agriculture. [PDF]
Yinjun Z.
europepmc +1 more source
Capital Growth: Precision Agriculture and Vertical Farming in the Corporate Food Regime
Justin Taylor
openalex +1 more source
This study reveals the genetic and molecular mechanisms controlling the general trade‐off between phenotypic mean and plasticity of grain chalkiness in rice and identifies two major external drivers (high temperature and wide grain) and a natural major module (GCP6‐MPC5) that control this trade‐off.
Juncheng Zhang +10 more
wiley +1 more source
Exploring the Functional Properties of Leaves of <i>Moringa oleifera</i> Lam. Cultivated in Sicily Using Precision Agriculture Technologies for Potential Use as a Food Ingredient. [PDF]
Greco C +14 more
europepmc +1 more source
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun +16 more
wiley +1 more source
The Delineation of Management Zones of the <i>Halyomorpha halys</i> (Hemiptera: Pentatomidae) Population Based on Its Spatiotemporal Distribution for Precision Agriculture Purposes. [PDF]
Liakos V +5 more
europepmc +1 more source

